Neurology Flashcards
Painful progressive axonal polyneuropathy with multi-organ dysautonomia, anti-Ro and anti-La negative, and electrophoresis is negative?
Amyloid Neuropathy, think about doing a biopsy
What is a good treatment for levodopa-cardopa dyskinesia?
Amantadine
Anti–muscle-specific kinase antibody is specific to what disease?
Myasthenia Gravis
Neuro symptoms plus Serum Gq1b antibody is specific to what?
Miller Fisher variant of GBS
Acute Migraine problem treatment with a benign physical exam is what?
Subcutaneous Sumatriptan
Postural Hypotension is common when what happens?
Assuming, no disasters, what is the best treatment?
Intracranial Hypotension
Epidural Blood Patch
If a patient is about to receive immunocompromising medication, when should vaccines be given?
4-6 weeks beforehand
Generalized tonic-clonic seizures are characterized by what?
Seizure episodes more than 5 minutes, or two in less than minutes without a return to a return neuro baseline
Myoclonic Seizures are characterized by what events?
Jerking, Shaking, less than 1 second, resulting in the patient falling down, no post-ictal lethargy or confusion
After Aortic Anuerysm repair, the patient has poor leg reflexes and paralysis, what happened?
Spinal Cord Infarction
Positive Myasthenia Gravis and symptommatic under 65 and 3 years of symptoms, what is the best treatment?
Surgery
Unexplained myopathy, what is an endocrine disorder?
Hypothyroidism
If a M.S. patient has been non-ambulatory for more than 2 years/no relapsing-readmitting activity what should be done?
Stop DMARDs and/or IFN medications
Ocrelizumab is approved for what?
Patients with relapsing-remitting M.S. and 1 progressive MS
What medication is good for migraine prophylaxis?
Venlafaxine
What aneurysm size can be watched in the brain?
Posterior Circulation less than 7mm, Anterior Circulation less than 12mm
If an IV drug user history patient has point tenderness on their L1, what is the next best step?
Imaging of the entire spine
If the patient has a right sided weakness and aphasia, elevated ABCD score, what should be done next?
Carotid Ultrasound
If a patient has bilateral essential tremor that is refractory to medication, what should be done next?
Deep Brain Simulation
What muscle abnormality is slow and sustained muscle contractions?
Dystonia
Brief, shock-like, and jerky movements that originate from any part of the nervous system system?
Myoclonus
Pharmacological intervention of FTD (Frontal Temporal Dementia) is what?
SSRI
A patient with new onset dementia in the past three years should have what?
MRI> CT scan
If a patient has drug resistant seizures and epilepsy, what is something that should be done before surgery?
Video EEG monitoring
If a patient has an obvious musculoskeletal deficiency, every female family member has it, what should we think about?
Mitochondrial Inheritance Pattern
Mitochondrial Myopathy
NIH stroke of 3, Minor stroke, elevated BP, what should be done with BP?
Goal BP is decrease amount 15% in the first 24 hours
Multiple Sclerosis with declining cognitive function, what should be done?
Cognitive therapy
_______________ include pain with eye movement, unilateral visual deficit, and an afferent pupillary defect
Optic Neuritis
Aneurysmal Subarachnoid hemorrhage, what is the best BP treatment?
Oral Nimodipine
Two signs of vascular cognitive impairment are what?
early gait impairment and personality/mood changes
If a patient does not have hippocampal atrophy and presence of confluent white matter hypersensitivities, what is the leading diagnosis?
Vascular Dementia
Stroke of an unknown origin, what is the next best outpatient step?
Ambulatory EKG monitor
Chronic tension type headaches can be treated with what?
Amitriptyline
What medication is recommended that there be no use with respect to headache management?
Butalbital
Onabotulinium toxin can be given for what neurology problem?
Chronic Migraine
If a patient has new brain lesions, unknown until currently, what should be done?
Brain Biopsy, no radiation
What is one bad mental health side effect that Keppra can cause?
Worsening of depression, anxiety, and suicidal ideation
Sustained or intermittent muscle contractions that are slow, repetitive, and directional?
Dystonia
What BP is needed in an ischemic stroke for alteplase treatment?
185/110
A patient has a meningoma, bad headaches, and some numbness/tingling. No seizures. What is the next best treatment?
Serial Brain MRIs
New onset seizure, Brain CT scan is wnl, what test should be ordered next?
Brain MRI
Neuromyelitis Optica is an inflammatory disorder of the central nervous system, affects the spinal cord and optic nerve. What is the antibody marker?
Aquaporin-4 antibody
Restless Leg Syndrome, what else should be evaluated?
Ferritin
A1c of 6.9, alcohol abuse and asymmetric sensory neuropathy, what is the most likely cause?
Diabetes
Tardive Dyskinesia is treated by what?
Valbenazine
What is the stenosis number needed to for intervention?
80%
Gait dysfunction in multiple sclerosis with ambulatory dysfunction, what should be given?
Dalfampridine
What is the chronic migraine drug of choice?
Erenumab
Post-stroke fatigue, what should be evaluated?
Polysomnography
Can an elderly patient withdraw from paroxetine?
Yes!
Chronic Cluster headaches should be treated how?
Subcutaneous Sumatriptan
A patient has a stroke, CT head is negative, no bleeding, on TPA, what is the next step for further evaluation?
CTA of the head, for further evaluation
Real time quaking induction assay is the test needed for what disease?
CJD Disease, 14-3-3 protein is not as sensitive or specific
When a patient has migraines and uses birth control, when should birth control pills be should they be stopped?
When a patient has an aura
If a patient has migraines that have not responded to NSAIDS over three attacks, what is the next recommendation?
Sumatriptan, assuming no CAD
Cancer, metastasis back pain, what is the best treatment?
Glucocorticoids and Radiotherapy
What are the guidelines for back surgery with cancer metastasis?
Must be less than 65, 6 months or longer of life, and a single area
Thunderclap headache, during sexual intercourse, known history of migraines, worse headache of their life, OTC dont make it better, CT brain is ordered, what is something that should be evaluated?
Berry Aneurysm Rupture
Donepizil can cause what cardio side effect?
Unintentional Bradycardia
Multiple Seziures back to back despite lorazepam, what is the next best drug?
Fosphenytoin
GBM surgery, s/p, what is the correct VTE?
SCDs, mechanical prophylaxis
Doxycycline treatment for acne with new onset headaches that are concerning for idiopathic intracranial HTN, what should be done?
Stop Doxycycline
S/P stroke, with TPA, no bleed, Neuro function is stable, what is another test to confirm neuro status?
Swallow Evaluation
TIA that has resolved after two minutes, what is the treatment regimen?
ASA and Plavix
Plavix only for 21 days
Parkison like symptoms plus visual hallucinations is what?
Treatment is what?
Lewy Body Dementia
Rivastigmine and Donepizil
A patient has a TIA, what is the scoring system to determine if he will have another stroke?
ABCD2 scoring system
Orthostatic hypotension with Cabidopa-Levodopa, what should be done?
Increase the dose, higher doses of medication help the side effects
Multiple Sclerosis patient, what thing should be done for annual wellness?
Flu vaccine
Anti-muscle specific kinase antibody measurement, what is this?
Myasthenia gravis
Atypical Bells palsy, involving multiple facial nerves, requires what other testing?
MRI evaluation
Frontotemporal Dementia and compulsive behaviors can be best treated how?
SSRI
Visual Blurring without diplopia, nocturnal pulsatile tinnitus, and neck stiffness -> including headache, physical exam includes bilateral papilledema, Lumbar puncture has elevated pressure, what disease is this with a young women?
Idiopathic Intracranial Hypertension
Mild to moderate Dementia with Alzheimer’s disease, what medication is prescribed?
Donepezil, Rivastigmine, and galantamine
Moderate to Severe Dementia with Alzheimer’s disease, what medication is prescribed?
Memantine is added on, acetylcholinesterase inhibitor, severe dementia is an MMSE < 10
A seizure episode where the patient describes a spasm, jerks, or shakes. This episode is usually bilaterally and happens for one second or less. Awareness is maintained during the seizures. What is this?
Myoclonic Seizures
What medical term means sustained or intermittent muscle contractions are slow, repetitive, and directional?
Dystonia
What medical term is random flowing patterns with regards to movement?
Chorea
Pyschogenic nonepileptic events are usually related to what?
PTSD or Conversion Disorder
Right sided aphasia, weakness, resolved after 1 minute, what is a common diagnosis to think about?
TIA
Patients with non-thrombolytic stroke treatment, what is the blood pressure treatment target and goal?
Treat when BP is above 220/120, only reduce 15% in the first 24 hours
After TPA, what is the goal BP?
180/105
If a person has a new seizure onset, they only had one seizure, the entire work up is negative, what is the next thing to do?
Brain MRI
Parkison + hallucination + Rapid eye movement + sleep disorder is what?
What meds can help?
Lewy body dementia
Rivastigmine and Donepezil
What are rapid, jerky, synchronous, and uniform movements, what is this?
Myoclonous
What is dystonia?
slow, sustained muscle contractions
Complex, coordinated, and ritualistic movements that are repeated in a prolonged cycle, is what? Usually related with developmental delay and neurometabolic syndromes
Sterotypy
If a patient has levo-dopa dyskinesia, i.e. levo-dopa wearing off quickly, what should be given next?
Amantadine
Homonogenous dural based lesion that has well-demarcated borders, minimal headaches and minor numbness and tingling, what is the best course of action?
Serial Brain MRIs
Hearing Loss
Tinnitus
Ear Pressure
Endolymph Hydrops
Horizontal Nystagmus
Vertigo symptoms last at least 20 minutes to 12-24 hours
Meniere’s Disease
Vertigo (Days to weeks)
No auditory Symptoms
Usually after Sick Contacts or Illness
Vestibular Nerve Infection
Horizontal Nystagmus
Vestibular Neuronitis or Viral Labyrinthitis
What are triggers for Meniere’s Disease?
Caffeine, Nicotine, EtOH, high salt intake, MSG, stress, food allergies, and environmental allergies
Vertigo
No auditory Symptoms
Triggered by Head Position
Rotary Nystagmus
Symptoms Last Seconds
BPPV, Benign Paroxysmal Positional Vertigo
What maneuver can help BPPV?
Dix Hall pike maneuver