Neurology

Question 1

Werdnig-Hoffman disease survival years

Answer 1

< 2

Question 2

Werdnig-Hoffman disease sits or walks?

Answer 2

None

Question 3

Which SMA can sit?

Answer 3

Type 2

Question 4

Severe muscle weakness (flaccid paralysis) and hypotonia in which SMA

Answer 4

Type 1

Werdnig-Hoffman disease

Question 5

Which SMA has near normal life expectancy?

Answer 5

Type III (Kugelberg-Welander disease)

Question 6

Onset of SMA 2

Answer 6

6-18m

Question 7

Duchenne muscular dystrophy Screening test:

Answer 7

Creatine kinase level

Question 8

Early sign of Duchenne muscular dystrophy:

Answer 8

Inability to walk independently until age >18 month

Question 9

Gowers sign indicates

Answer 9

Duchenne muscular dystrophy

Question 10

Calf psuedohypertrophy seen in

Answer 10

Duchenne muscular dystrophy

Question 11

Duchenne muscular dystrophy treatment

Answer 11

Glucocorticoids

Question 12

Duchenne muscular dystrophy is (inheritance type)

Answer 12

X linked recessive

Question 13

How do Duchenne muscular dystrophy die?

Answer 13

Resp/heart failure in 20s

Question 14

We suspect patient has cerebral palsy when:

Answer 14

Definite hand preference before 1 year of age + Persistent moro reflex

Question 15

Management of CP

Answer 15

Baclofen and botulinum

Question 16

Status epilepticus management

Answer 16

—-

Question 17

How to tell if patient is seizing

Answer 17

Tachycardia
Desating
Fixed dialated pupils

Question 18

Child absence seizure EEG

Answer 18

3 hz spikes

Question 19

Child absence seizure treatment

Answer 19

Ethosuxemide

Question 20

Benign ronaldic epilepsy EEG

Answer 20

Centrotemporal spikes

Question 21

Infantile spasm EEG

Answer 21

Hyparrythmia

Question 22

West syndrome triad

Answer 22

1- Hypsarrythmia
2- Infantile spasm
3- Developmental delay

Question 23

Most common partial epilepsy of childhood

Answer 23

Benign Rolandic Epilepsy

Question 24

Treatment of stroke in general population

Answer 24

Antiplatelet/anticoagulant

Question 25

Treatment of stroke in cardiac patients

Answer 25

anticoagulant

Question 26

Treatment of stroke in SCD

Answer 26

Hydration | Exchange transfusion

Question 27

Focal seizure classification

Answer 27

If impaired consciousness: Complex | If no impaired consciousness: Simple

Question 28

Generalized seizure types

Answer 28

``` Tonic clonic Myoclonic Tonic Atonic Absence ```

Question 29

Most common casues of febrile seizure (in order):

Answer 29

Acute respiratory illness > Gastroenteritis (Shigella, Campylobacter) > UTI

Question 30

Miller Fisher Syndrome symptoms

Answer 30

* Stoking-gloving periphral neuropathy * Opthalmoplegia & ptosis * ataxia + areflexia + dysmetria on heel-to-shin testing

Question 31

Which syndrome is immune-mediated polyneuropathies

Answer 31

Miller Fisher Syndrome/GBS

Question 32

Miller Fisher Syndrome Tx

Answer 32

Plasmapheresis & IVIG

Question 33

- Next step in hemodynamically stable in GBS:

Answer 33

1. Spirometry (to monitor respiratory function) | 2. If FVC<20ml/kg : Intubation

Question 34

Progressive ascending symmetric muscle weakness

Answer 34

GBS

Question 35

Deep tendon reflexes in GBS

Answer 35

Absent/depressed deep tendon reflexes

Question 36

Dx of cerebral palsy

Answer 36

MRI

Question 37

GBS dx

Answer 37

Clinical and LP: Albuminocytologic

Question 38

Transverse myelitis dx

Answer 38

Clinically (bilaterla motor & snesory weakness) + MRI (enhancement of affect cord without compression) + LP CSF (pleocytosis & elevated IgG)

Question 39

Transverse myelitis Tx

Answer 39

IV steroid + Plasmapheresis

Question 40

Which has occular weakness (GBS/MG)?

Answer 40

MG

Question 41

Which has depressed tendon reflexes? (GBS/MG)

Answer 41

GBS

Question 42

Fatiguability of proximal muscle weakness

Answer 42

Myasthenia gravis

Question 43

Myasthenia gravis affect:

Answer 43

Occular Bulbar Resp

Question 44

Myasthenia gravis Tx

Answer 44

AChE inhibitors | Pyridostigmine

Question 45

Myasthenia gravis dx

Answer 45

AchR Ab | Ice pack test

Question 46

Transverse myelitis Tx

Answer 46

IV steroid + Plasmapheresis

Question 47

Thymoma is associated with which neurological condition

Answer 47

MG

Question 48

Tuberus scelerosis is autosomal

Answer 48

Dominant

Question 49

Tuberus scelerosis Sx

Answer 49

Derm: Ashleaf spots, Angiofibroma Neuro: CNS lesions Renal: Angiomyolipoma

Question 50

NF criteria

Answer 50

``` 2 or more present: 2 or more NF 6 cafe au lait spots Axillary freckling Lisch nodules Glioma First degree relative with NF ```

Question 51

Bilateral acoustic neuroma is present with

Answer 51

NF2

Question 52

Lower motor neuron lesion affects

Answer 52

Upper and lower sides of face

Question 53

Upper motor neuron lesion affects

Answer 53

Lower side of face