Hematology Flashcards

1
Q

Labs in iron deficiency anemia

A

Iron L
Ferritin L
TIBC H

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2
Q

Labs in anemia of chronic disease

A

Iron L
Ferritin H
TIBC L

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3
Q

How to diagnose thalassemia

A

Hemoglobin electrophoresis

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4
Q

Treatment for thalassemia

A

Major thalassemia transfusion

Minor thalassemia nothing

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5
Q

Diagnosis of sideroblastic anemia

A

Ringed sideroblasts in BM bx

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6
Q

1st Test for G6PD

A

blood smear:

Bite cells and Heinz body

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7
Q

Best test for auto immune hemolysis

A

Coombs test

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8
Q

Best test for hereditary spherocytosis

A

Osmotic fragility

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9
Q

Splenectomy is done for which conditions

A

Hereditary spherocytosis

Auto-immune hemolysis

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10
Q

Treatment for sideroblastic anemia

A

B6

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11
Q

MMA is elevated with

A

B12 def

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12
Q

If lead is > 70ug/dL:

A

Hospitalization + 2 IV drugs (EDTA + Dimercaprol/British anti-lewisite)

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13
Q

Lead level of >45ug/dL

A

Start chelation therapy

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14
Q

Confirm diagnosis of lead poisoning

A

Venous lead sample

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15
Q

Lead poisoning screening

A

Capillary blood sample

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16
Q

Sequestration crisis labs

A

Low plt
Low hg
High retics

17
Q

Treatment for aplastic crisis

A

transfusion

18
Q

Treatment for sequestration crisis

A

transfusion

19
Q

Treatment for vaso-occlusive crisis

A

Hydration

20
Q

Sickle cell patient with new infiltration of chest

A

Acute chest syndrome

21
Q

TTP

A
TheTerrible Pentad:
1- Fever
2- Neurologic
3- Renal
4- Anemia
5- Platelets (thrombocytopenia)
22
Q

Cells see. In TTP

A

Schistiocytes

23
Q

HUS

A

Hemolysis
Uremia
Stomach virus
Thrombocytopenia

24
Q

Went to give antibiotics in HUS

A

Contraindicated.

25
ITP labs
Isolated thrombocytopenia
26
Chronic ITP:
Low plts for more than 12 months
27
Rh positove vs negative ITP
Rh negative blood patient Tx: IVIG Rh positive blood patient Tx: Anti-D immune globulin
28
When to treat ITP
Plt < 10k or bleeding
29
Dec in ADAMTS level
TTP
30
Tx of vWF
Desmopressin
31
Hemophilia, Tx:
- Mild bleeding: Desmopressin (DDAVP) | - joint/severe bleeding: factor replacement
32
Bleeding time in vWF
Increased
33
Fanconi anemia Tx
Stem cell transplant
34
Triphalangeal thumb present in
Diamond blackfan anemia
35
Diamond blackfan anemia Tx
RBC tranfusion and steroids
36
ADA is high in fanconi or blackfan
Diamond blackfan anemia
37
Bone marrow of fanconi
Bone marrow failure