Hematology Flashcards

1
Q

Labs in iron deficiency anemia

A

Iron L
Ferritin L
TIBC H

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2
Q

Labs in anemia of chronic disease

A

Iron L
Ferritin H
TIBC L

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3
Q

How to diagnose thalassemia

A

Hemoglobin electrophoresis

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4
Q

Treatment for thalassemia

A

Major thalassemia transfusion

Minor thalassemia nothing

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5
Q

Diagnosis of sideroblastic anemia

A

Ringed sideroblasts in BM bx

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6
Q

1st Test for G6PD

A

blood smear:

Bite cells and Heinz body

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7
Q

Best test for auto immune hemolysis

A

Coombs test

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8
Q

Best test for hereditary spherocytosis

A

Osmotic fragility

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9
Q

Splenectomy is done for which conditions

A

Hereditary spherocytosis

Auto-immune hemolysis

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10
Q

Treatment for sideroblastic anemia

A

B6

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11
Q

MMA is elevated with

A

B12 def

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12
Q

If lead is > 70ug/dL:

A

Hospitalization + 2 IV drugs (EDTA + Dimercaprol/British anti-lewisite)

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13
Q

Lead level of >45ug/dL

A

Start chelation therapy

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14
Q

Confirm diagnosis of lead poisoning

A

Venous lead sample

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15
Q

Lead poisoning screening

A

Capillary blood sample

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16
Q

Sequestration crisis labs

A

Low plt
Low hg
High retics

17
Q

Treatment for aplastic crisis

A

transfusion

18
Q

Treatment for sequestration crisis

A

transfusion

19
Q

Treatment for vaso-occlusive crisis

A

Hydration

20
Q

Sickle cell patient with new infiltration of chest

A

Acute chest syndrome

21
Q

TTP

A
TheTerrible Pentad:
1- Fever
2- Neurologic
3- Renal
4- Anemia
5- Platelets (thrombocytopenia)
22
Q

Cells see. In TTP

A

Schistiocytes

23
Q

HUS

A

Hemolysis
Uremia
Stomach virus
Thrombocytopenia

24
Q

Went to give antibiotics in HUS

A

Contraindicated.

25
Q

ITP labs

A

Isolated thrombocytopenia

26
Q

Chronic ITP:

A

Low plts for more than 12 months

27
Q

Rh positove vs negative ITP

A

Rh negative blood patient Tx: IVIG

Rh positive blood patient Tx: Anti-D immune globulin

28
Q

When to treat ITP

A

Plt < 10k or bleeding

29
Q

Dec in ADAMTS level

A

TTP

30
Q

Tx of vWF

A

Desmopressin

31
Q

Hemophilia, Tx:

A
  • Mild bleeding: Desmopressin (DDAVP)

- joint/severe bleeding: factor replacement

32
Q

Bleeding time in vWF

A

Increased

33
Q

Fanconi anemia Tx

A

Stem cell transplant

34
Q

Triphalangeal thumb present in

A

Diamond blackfan anemia

35
Q

Diamond blackfan anemia Tx

A

RBC tranfusion and steroids

36
Q

ADA is high in fanconi or blackfan

A

Diamond blackfan anemia

37
Q

Bone marrow of fanconi

A

Bone marrow failure