Neonatology Flashcards
RDS is ___ deficiency
Surfactant
Age at risk for RDS?
Preterm
Age at risk for TTN
Usually term
How does TTN happen?
Delayed resorption of fetal lung fluid
TTN CXR
Wet silhouette, fluid in fissures
Risk factor for TTN
Short labour, Elective CS
CXR in RDS
Homogenous infiltrates, Air bronchogram, Groundglass appearance
RDS prevention?
Corticosteroids prenatally
RDS treatment
Surfactant
MAS treatment
inhaled NO
MAS CXR
Patchy atelectasis
What ratio indicates lung maturity?
Lecithin/Sphinngomyelin ratio > 2:1
Fluid in fissures appears in
TTN
Complication of MAS
Pneumothorax
BRUE is >1 of:
1-Cyanosis
2-Change of tone
3-Absent/irregular breathing
4-Altered level of responsiveness
Red flags of BRUE
1- <60 days 2-Unwell upon exam 3->1 episode 4->1min 5-Born<32weeks 6-FH SIDS
BRUE low risk management
Observe 1-4 hrs, Pertussis PCR, outpatient visit
Physiologic Jaundice appears on __ day, and disappears on __ day
2-3, 7th
Physiologic Jaundice’s peak is __ mg/dL
<13 mg/dL (if term)
Physiologic Jaundice’s rate of bilirubin’s rise is __ mg/dL/d
<5 mg/dL/d
Pathological Jaundice’s rate of bilirubin’s rise is __ mg/dL/d
> 5 mg/dL/d
Pathological Jaundice appears in ___ day
First 24 hrs of life
Unconjugated bilirubin features:
Lipid soluble, crosses BBB
No urine excretion, Kernicterus
Conjugated bilirubin features:
Water soluble, Doesn’t cross BBB,
No kernicterus, + urinary excretion
Where does unconjugated bilirubin accumulate causing kernicterus?
Basal ganglia and brain stem nuclei
Kernicterus leads to _____
Sensorineural hearing loss
If jaundice was indirect, what do we think ?
Coombs + or -
Breastfeeding jaundice
- Feeding inadequate, baby dehydrated
- First time mothers
- First week of life
- Tx is breastfeeding education
Breast milk jaundice
- Problem in the MILK
- Feeding is adequate
- Second week of life, resolve by 2-3m
- Tx is phototherapy
How to deliver glucose concentration of > 12.5% in neonate with hypoglycemia?
Via central line
Biliary atresia initial test
RUQ US
Biliary atresia initial management
Kasai
Biliary atresia definitive management
Liver transplant
Type of jaundice in Biliary atresia?
Direct hyperbilirubinemia
Biliary atresia pathogenisis
Extrahepatic bile duct fibrosis
US of biliary atresia shows:
Absent/abnormal gallbladder and CBD
Cow milk deficient in
Iron, Copper, Vit C
Human milk deficient in
Vit D and Riboflavin
Caput Succedeum
Crosses suture lines
Disappears in a few days
Maximum size at birth
Cephalhematoma
Doesn’t cross suture lines
Resolves in 2 wks
Maximum size 1d after birth
Coloboma association
CHARGE
Early introduction of cow’s milk leads to
Iron deficiency anemia
When do breastfed infants need iron?
> 4 m
Newborn growth rate in grams
30 g/day
Which Ig present in colostrum?
IgA
Do not brrastfeed
Do not give expressed milk
1- Mother has HIV 2- Mother has Ebola 3- Mother has Human T-lymphotropic virus 4- Mother uses illicit drugs 5- Child has Galactosemia
Do not brrastfeed
Do not give expressed milk
(Temporarily)
Mother has untreated Brucellosis
Mother has HSV w/ lesions on breast
Mother is taking certain meds
Temporarily do not breastfeed, expressed is okay
Untreated active TB
Varicella (developed bw 5 days prior to delivery and 2 days following delivery)
Human milk stays in freezer for
6m