Neuroembryology ppt 8 Flashcards
How is the neural tube formed?
Formed as the neural folds fuse in the midline and separate from the surface ectoderm
What does the neural tube give rise to?
the CNS
- The cranial part becomes the brain. brainstem
- The caudal part becomes the spinal cord.
What forms from the cavity of the neural tube?
the central canal of the spinal cord and the ventricles in the brain
When do the opening in the neural tube close?
- Anterior neuropore: closes in the fourth week (day 25) and becomes the lamina terminalis.
- Posterior neuropore: closes in the fourth week (day 27).
What does the basal plate become?
Ventral Horn MOTOR neurons
ventral gray columns, nut of CN XI
What does the the alar plate become?
Sensory dorsal horn
dorsal gray columns
What are the neural crest cells?
- Derived from ectodermal cells.
- migrate and give rise to multiple adult derivatives
What are the primary vesicles of the brain?
Forebrain (prosencephalon)
Midbrain (Mesencephalon)
Hindbrain (rhombencephalon)
What secondary vesicles derive from the Prosencephalon?
Telencephalon
Diencephalon
What adult derivative comes from the telencephalon
Tissue- Cerebral hemispheres
Cavity- Lateral ventricles
What are the adult derivatives of the diencephalon?
Tissue- Thalamus and hypothalamus
Cavity- most of the 3rd ventricle
What are the secondary vesicles of the mesencephalon?
What are the adult derivatives?
Mesencephalon
Tissue- Midbrain
Cavity- Aqueduct
What are the secondary vesicles of the rhombencephalon?
Metencephalon
Myelencephalon
What are the adult derivatives of the metencephalon?
Tissue- Pons and Cerebellum
Cavity- 4th ventricle
What are the adult derivatives of the myelencephalon?
Tissue- Medulla
Cavity- 4th ventricle
What divides the basal and alar plates?
Sulcus Limitants