Neurodevelopmental disorders: schizophrenia

Question 1

Is schizophrenia more frequent and severe in men

Answer 1

Yes

Question 2

Schizophrenia is most commonly diagnosed in __ and __ decade of life; peaks around age __-__

Answer 2

2nd-3rd decade

18-25

Question 3

Do those with schizophrenia have shorter life spans? What is responsible for this in earlier years vs later yeras?

Answer 3

Yes, suicide and CVD

Question 4

4 categories of symptoms?

Answer 4

Positive symptoms (fluctuates)
Negative symptoms (fluctuates)
Cogntiive symptoms (stable)
Mood symptoms

Question 5

What do positive symptoms include?

Answer 5

Delusions
Hallucinations
Disorganised thoughts, speech, behaviour

Question 6

Do you need to know other symptoms?

Answer 6

Yes

Question 7

Do you need to know DSM and ICD10 diagnoses?

Answer 7

Yes

Question 8

Do you need to know genetic and environmental risk factors?

Answer 8

Yes

Question 9

BEst supported candidate gene?

Answer 9

DISC1

Question 10

Describe volume of grey/white matter, and total volume

Answer 10

All degreased

Question 11

Striatal connectivity to the prefrontal cortex, and consequences?

Answer 11

Abnormalities –> accounts for positive and negative symptoms

Question 12

Describe dorsolateral prefrontal cortex, anterior cingulate cortex, and inferior parietal lobe, and conseqence?

Answer 12

Abnormalities –> executive dysfunction

Question 13

What are the 5 theories of schizophrenia? Do you need to know in detail

Answer 13

Mental illness
Imbalance of brain chemistry (dopanmine)
Neurodevelopmental disorder 
Neurochemical changes
Two hit hypothesis 

yes

Question 14

Two types of drug treatments

Answer 14

Typical/first gen antipsychotics

Atypical/second gen antipsychotics

Question 15

Two types of counselling

Answer 15

CBT and supportive psychotherpay

Question 16

Do you need to know about animal models

Answer 16

yes