Neurodevelopmental Disorders and Psychopharmacology Lecture

Question 1

what is a medical issue specifically associated with down syndrome

Answer 1

thyroid disease

Question 2

what is a medical issue specifically associated with cornelia de lange syndrome

Answer 2

GERD

Question 3

what is the psychiatric syndromes associated with fragile X

Answer 3

ADHD, ASD

Question 4

list 3 antidepressants with high risk for reducing seizure threshhold/precipitating seizures

Answer 4

buproprion

clomipramine

maprotiline

Question 5

name two antipsychotics that are high risk for reducing seizure threshhold/precipitating seizures

Answer 5

clozapine

chlorpromazine

Question 6

in which genetic disorders should you be careful about Rx meds that lower seizure threshold (due to high rates of epilepsy in these disorders)

Answer 6

Angelman

Tuberous Sclerosis

Down syndrome

Fragile X

Rett syndrome

Wolf-Hirschorn

Question 7

which treatments for ADHD have RCT evidence use in those who also have ASD

Answer 7

methylphenidate

atomoxetine

guanfacine

clonidine

Question 8

what is a medication class that may have “challenging behaviour” as a side effect

Answer 8

anticonvulsants