Neurocognitive Disorders Flashcards
What is the neuropathology of Alzheimer’s?
Neutrons in the brain secrete a sticky protein called beta amyloid. This accumulates into amyloid plaque. Triggers chronic inflammation and releases cytokines, kills brain cells. Basically it involves 3 things: cell loss, plaque and neurofibrillary tangles
What forms of Neurocognitive disorders are recognised in DSM-5? What is presumed to be the cause of these disorders?
DSM-5 recognises major and mild forms of disorders as well as delirium from the result of transit or permit damage to the brain; chronic disorders is the permanent loss of neuro cells
What are the clinical features of Neurocognitive disorders?
There is major - which is the loss of function of skills that are during course can be slow or gradual the most major cause of your comment disorder is Alzheimer’s disease
Or relationship- Some people who have severe damage develop no symptoms were somewhat slight damage have extreme reactions
What is delirium and how is it treated?
Delirium has a sudden onset. Common among the elderly, it is characterised by state of awareness that fluctuates between wakefulness and stupor: coma. Delirium is treated with Neroleptic medications and also with benzodiazepines
What is the risk factors for Alzheimer’s disease?
Age is a major risk factor as well as other forms of dementia such as vascular dementia. Genes play a major role in susceptibility to and risk for. genetic mutations consist of the APP, PS1, and PS2 genes. the APOE-E4 is also a risk factor for Alzheimer’s disease
How is Alzheimer’s disease treated?
The disease causes the destruction of cells. treatments include cholestrease inhibitors. These stop ACH from being broken down and so make it more available for the brain. also caregivers that deal with stress may benefit from medications and support groups
What is an amnesiac disorder? What causes that these
disorders involve severe memory loss most common is chronic alcohol abuse. Other causes include head trauma/surgery infections and hypoxia
What are the clinical consequences of head trauma?
Head injuries can cause amnesia as well as other cognitive impairment. Retrograde amnesia is inability to recall events that pre-seeded the trauma anterograde amnesia is inability to remember things that follow it.
What factors are related to the degree of impairment that results in head trauma?
Inconsistencies are not completely understood, it appears that individuals pre-morbid personality and life situation is important into determining reactions to brain damage. The APOE-E4 genetic allelle is also important. The severity of the trauma age of the person and sight of the injury are also important.
How is amnesia disorder diagnosed in DSM-5?
Previously the disorder was a specific and distinct diagnosis. DSM/5, patients would have been given this diagnosis will now be diagnosed as having a major Nero cognitive disorder
