Neurochemistry and Neuropharmacology Flashcards
is a chemical released by the presynaptic terminal button in response to an action potential
Neurotransmitter
briefly binds to a specialized protein called a receptor that is located on the postsynaptic membrane
Neurotransmitter
attaches to a receptor like a key fitting into a lock
Neurotransmitter
has criteria including the following: its synthesis is within a neuron, it is released in response to a neuronal depolarization, and it binds to a postsynaptic receptor
Neurotransmitter
the following are examples of this: acetylcholine, dopamine, norepinephrine, epinephrine, serotonin, glutamate, GABA, endocannibinoid, and endogenous opioid
Neurotransmitter
type of receptor that, when stimulated, immediately opens an ion channel
Ionotropic receptor
type of receptor that is associated with a ligand-activated ion channel
Ionotropic receptor
type of receptor that, when stimulated, does not immediately open an ion channel
Metabotropic receptor
type of receptor that is associated with signal proteins and G proteins
Metabotropic receptor
is the drawing back, into the presynaptic button, neurotransmitter molecules after their release into the synapse
Reuptake
is the more common of the two mechanisms for deactivating released neurotransmitters
reuptake
is the breakdown of neurotransmitters by enzymes
enzymatic degradation
is the less common of the two mechanisms for deactivating released neurotransmitters
enzymatic degradation
is the most prevalent excitatory neurotransmitter in the brain
glutamate
is one of the amino acid neurotransmitters that is common in the proteins we consume
glutamate
overstimulation by this neurotransmitter can be toxic, causing cell death
glutamate
is the most prevalent inhibitory neurotransmitter in the brain
GABA
neurotransmitter that is synthesized by a simple modification of the structure of glutamate
GABA
neurotransmitter that alcohol acts primarily as an agonist of in the brain so that at moderate doses it causes cognitive, perceptual, verbal, and motor impairments, even though at low doses it can facilitate social interaction
GABA
an excessive decrease in this neurotransmitter can result in convulsions and possibly death
GABA
agonists of this neurotransmitter are used to treat seizures and other disorders such as anxiety and insomnia
GABA
neurotransmitter that naturally converts into norepinephrine
Dopamine
neurotransmitter that has been implicated in the pathology of both Parkinson’s disease and schizophrenia
Dopamine
neurotransmitter that plays an important role in the control of motor movement and in motivational aspects of drug use
Dopamine