Neuro6 - 12

Question 1

Describe the neural tube initially

Answer 1

Single layered neuroepithelium

Question 2

What do some cells in the neural tube do?

Answer 2

Span the width

Question 3

What do cells that span the width of the neural tube do?

Answer 3

Migrate back and forth at different stages of mitosis

Question 4

What are the cells that span the width of the neural tube called?

Answer 4

Radial glia, later becoming neural stem cells

Question 5

Where does the division of radial glia occur?

Answer 5

Lumen

Question 6

Where do radial glia oscillated between?

Answer 6

Lumen and ventricular zones

Question 7

Where do differentiated radial glia daughters migrate to?

Answer 7

Through mantle zone into marginal zone

Question 8

Where do proliferating progenitors proliferate?

Answer 8

Mantle zone

Question 9

What determines differentiated/stem cell remaining balance?

Answer 9

Delamination, which is controlled by proneural genes, controlled by Delta-Notch

Question 10

How does delta-notch control proneural gene expression?

Answer 10

Juxtacrine lateral inhibition

Question 11

Outline histogenesis of cerebral cortex

Answer 11

Preplate - Cajal-Retzius cells + sub plate. Sub plate > intermediate zone. Cajal-retzius cells > marginal zone. Addition of cortical plate between marginal and intermediate