Neuro5 - 8 Flashcards
When does neural crest formation and neural tube patterning happen?
Before SHh expression in the notochord
What form at the interface of the induced neural plate and the surface ectoderm?
Neural plate border cells - progenitors to later become neural crest cells and roof plate cells
What does the border between neural plate and surface ectoderm secrete?
BMPs and Wnts
When are BMPs and Wnts secreted in the neural plate?
Before SHh, so neural tube actually dorsal in character first
What kinds of morphogen is BMP?
Temporal
What are neural crest cells sometimes referred to as?
4th germ layer
Neural crest cells differentiate into
Adrenal medulla, melanocytes, facial cartilage, dentine of teeth, PNS - schwann cells, neuroglial cells, SS, PSS
Neural tube differentiates into
brain, neural pituitary, spinal cord, motor neurons, retina