Neuro8 - 15

Question 1

Three sensory organ origins

Answer 1

Neural cres, neural tube, placodes

Question 2

Characterise c. elegans mechanireceptors

Answer 2

Gentle to harsh body touch sensitivity

Question 3

Outline c. elegans touch cell lineage

Answer 3

Q cell > Q1p > GBT cell > gentle body touch

Question 4

What is turned on in Q1p?

Answer 4

UNC-86, then MEC-3

Question 5

What are SOPs?

Answer 5

Sensory organ precursors (drosophila)

Question 6

What do SOPs for external receptors express?

Answer 6

Ct

Question 7

What forms a single innervated sensilla?

Answer 7

4 daughters of SOP from 2 divisions

Question 8

Outline the single-innervated sensilla lineage

Answer 8

SP > SPIIA + SPIIB > (support + neuron) + (socket + shaft)

Question 9

What is involved in SIS differentiation?

Answer 9

NUMB (protein), inhibiting notch

Question 10

What does bride of sevenless induce in drosophila eyes?

Answer 10

R7 becomes a photoreceptor, not a cone

Question 11

Where does the vertebrate eye develop from?

Answer 11

Neural and non neural ectoderm - ventricular progenitors produce types in sequence, with ganglion cells first

Question 12

Where does the vertebrate ear develop from?

Answer 12

Otic placode - from otic pit to otic vesicle, then otocyst. VIII ganglion is placodal

Question 13

Outline notch involvement in hair cell development

Answer 13

High - support cells; low - hair

Question 14

Where are olfactory bulb neurons generated from?

Answer 14

Subventricular zone