neuro 21 Flashcards

1
Q

Kernig’s sign

A

pain upon attempted passive extension at the knee when the hip is flexed

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2
Q

Brudzinski’s sign

A

involuntary flexion of the hip when the neck is flexed

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3
Q

treatment of brain abscess

A

prolonged courses of IV antibiotics are mainstay;

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4
Q

why is LP contraindicated in spinal epidural abscess before you know the exact location?

A

possibility of seeding the subarachnoid space with bacteria using the spinal needle

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5
Q

treatment of epidural abscess

A

prolonged IV antibiotics

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6
Q

how does TB meningitis differ from normal bacterial meningitis?

A

TB has a predilection for the basal meninges and thus can present with CN palsies in addition to usual features of meningitis; also TB is more subacute or chronic, with prolonged prodrome

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7
Q

basal meningitis

A

more commonly leads to hydrocephalus or brain infarcts from inflamm affecting the cerebral vessels

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8
Q

how is CSF in TB meningitis different from bacterial?

A

leukocytosis w lymphocytic predominence not PMNs; CSF glucose is even lower

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9
Q

tuberculoma

A

mass lesion caused by TB

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10
Q

Pott disease

A

TB of the spine

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11
Q

when do neuro symptoms of lyme disease appear?

A

several weeks after the bite

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12
Q

neuro findings in lyme disease

A

headache, stiff neck, myalgias, CN palsies (most commonly facial nerve), polyradiculopathy (with pain), polyneuropathy, enecephalopathy

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13
Q

CSF in lyme disease

A

lymphocytic pleocytosis wth elevated protein and normal glucose

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14
Q

MRI of the brain in lyme encephalopathy

A

patchy foci of signal change in the white matter

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15
Q

treatment of neuro lyme

A

if negative CSF, treat with oral antibiotics; more disem neuro infection requres IV antibiotics

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16
Q

viral meningitis is commonly caused by what organisms?

A

enteroviruses, such as Coxsackie virus, or arbovirus such as West Nile virus

17
Q

HSV1 encephalitis differs from general encephalitis how?

A

HSV has a predilection for the base of the brain, specifically the medial temporal lobes and orbitofrontal regions

18
Q

CSF in HSV1 encephalitis

A

elevated RBC count in addition to leukocytosis

19
Q

treatment for HSV1 encephalitis

A

prolonged IV course of acyclovir

20
Q

most common form of fungal meningitis

A

crypto

21
Q

CSF profile in crypto meningitis

A

lymphocytic predominance of white blood cells, elevated protein, and low glucose; this pattern is seen with all fungal meningitis

22
Q

imaging studies of toxo of the brain

A

multiple rign-enhancing lesions in the basal gang or at the gray matter-white matter junction

23
Q

neurocystcercosis

A

infection caused by the pork tape work Taenia solium

24
Q

where is neurocysticercosis endemic?

A

cental and south america; so commonly seen in immigrant populations in the US

25
Q

how does neurocysticercosis present

A

seizures, headahce, and sigs of increased ICP

26
Q

treatment for neurocysticercosis

A

albendazole and steroids; anticonvulsants to control the seizures

27
Q

HIV associated dementia

A

late complication of HIV; subcortical dementia, with cognitive impairment and psychomotor slowing

28
Q

cytoalbuminologic dissociation in CSF

A

guillan- barre

29
Q

valcyclovir

A

only available in oral form