neuro 19

Question 1

most common tumors in the CNS

Answer 1

mets from distant neoplasms

Question 2

NF1 assoc with what type of brain tumor

Answer 2

glioma (optic nerve) and ependymoma

Question 3

NF2 assoc with what type of brain tumor

Answer 3

meningioma and glioma

Question 4

von Hippel-Lindau assoc with what type of brain tumor

Answer 4

hemangioblastoma

Question 5

Li-fraumeni cancer family syndrome assoc with what type of brain tumor

Answer 5

glioma and medullablastoma

Question 6

most impt prognostic factors for brain tumors

Answer 6

histologic type and age

Question 7

most common primary brain tumors

Answer 7

gliomas and meningiomas

Question 8

four types of gliomas

Answer 8

astrocytoma, oligodendroglioma, ependymoma, and choroid plexus papilloma

Question 9

GBM (glioblastoma multiforme)

Answer 9

this is a grade 4 astrocytoma

Question 10

low grade gliomas

Answer 10

grade I and II astrocytomas

Question 11

genetic signature of oligodendroglioma

Answer 11

co-deletion of chromosomal arms 1p and 19 q

Question 12

fried egg appearance (perinuc halos with swollen cytoplasm)

Answer 12

oligodendrogliomas

Question 13

ependymoma

Answer 13

arises from the ependymal lining of the ventricles

Question 14

perivascular pseudorosettes

Answer 14

a halo of cells surrounding a central vascular lumen; hallmark of ependymoma

Question 15

CSF is where

Answer 15

subarachnoid space

Question 16

meninigiomas are usually benign

Answer 16

right

Question 17

origin of medullablastoma

Answer 17

medullary velum o fthe fourth ventricle; up to 30% from the cerebellar hemispheres