neuro Flashcards

1
Q

what is a TIA

A

reverses after 24 hours

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2
Q

what controls ICP

A

IV mannitol

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3
Q

1st investigation when suspecting stroke

A

CT HEAD

determine whether ischaemic or haemorrhagic

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4
Q

key symptom of subarachnoid haemorrhage

A

thunderclap headache

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5
Q

what would a lumbar puncture show in a subarachnoid haemorrhage

A

red blood or xanthochromia

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6
Q

treatment for subarachnoid haemorrhage

A

nimodipine

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7
Q

what is typically ruptured in a subdural haematoma

A

bridging veins

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8
Q

when does a subdural haematoma present

A

often delayed onset of symptoms

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9
Q

what shape on a CT is a subdural haematoma

A

crescent shaped

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10
Q

what is typically affected in an extradural haemorrhage

A

middle meningeal artery

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11
Q

what happens in an extradural haemorrhage

A

lucid interval

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12
Q

what shape on a CT is a extradural haemorrhage

A

convex shape

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13
Q

causes of a migraine

A
CHOCOLATE
chocolate
hangovers
orgasms
cheese
oral contraceptive pill
lie-ins
alcohol
tumult
excercise
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14
Q

treatment for a migraine

A

sumatriptan

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15
Q

where is the pain in a cluster headache

A

localised around the eye

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16
Q

what syndrome is associated with a cluster headache

A

horner’s syndrome

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17
Q

what is horners syndrome

A
miosis = constricted pupil
ptosis = droopy eyelid
anhidrosis = decreased sweating
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18
Q

what is the difference between a simple partial and complex partial seizure

A

consciousness is impaired during a complex

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19
Q

what are the 6 types of generalised seizures

A
tonic
atonic
clonic
tonic-clonic
absence
myoclonic
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20
Q

which seizure involves stiffness

A

tonic

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21
Q

which seizure involves relaxation

A

atonic

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22
Q

which seizure involves jerking/convulsions

A

clonic

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23
Q

which seizure involves short muscle twitches

A

myoclonic

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24
Q

which seizure is known as being ‘spaced out’

A

absence

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25
what time is classes as status epilepticus
>5mins
26
what is the most common type of primary brain tumour
astrocytoma
27
what causes alzheimers
build up of beta amyloid plaques
28
medication for alzheimers
rivastigmine
29
what type of progression is vascular dementia
step wise progression
30
treatments for parkinson's
levodopa COMT-inhibitors MAO-B inhibtors
31
what inheritance pattern is Huntington's disease
autosomal dominant
32
what is the triplet repeated in Huntingtons
CAG
33
How many times minimum is CAG repeated in huntingtons
36
34
what chromosome is affected in Huntington's
4
35
Where is fine touch, pressure, vibration and proprioception lost in Brown-Sequard syndrome
same side as the lesion
36
where is pain, temperature and crude touch lost in Brown-Sequard syndrome
opposite side of lesions, 1 or 2 segments below
37
what is caudal equina symptoms also known as
saddle anaesthesia
38
what nerve is compressed in carpal tunnel syndrome
median
39
what muscles can waste away in carpal tunnel syndrome
thenar
40
What is the most common type of motor neurone disease
ALS
41
does ALS affected UMNs, LMNs or both
both
42
does Progressive bulbar palsy affect UMNs, LMNs or both
LMNs in the brain stem
43
what cells are affected in MS
oligodendrocytes
44
what is typically the first sign of MS
optic neuritis
45
what is the gold standard investigation for MS
MRI
46
what usually causes Guillain-Barre syndrome and give 3 examples
Post-GI infection | campylobacter jejuni, EBV, CMV
47
what type weakness is seen in Guillain-Barre syndrome
toes to nose (symmetrical)
48
treatment for Guillain-Barre syndrome
IVIgG
49
What does Lambert Eaton syndrome usually present with
small cell lung cancer
50
what is the key sign of Myasthenia gravis
weakness that is worse on exertion
51
what drug can control symptoms of Myasthenia gravis
pyridostigmine
52
what is kernigs sign
painful extension of hip when leg at 90 degrees
53
what 2 drugs can be given for a partial/focal seizure
lamotrigine | carbamazepine
54
what drugs can be given for a myoclonic seizure
sodium valproate | levetiracetam/topiramate for females of child bearing potential
55
what drugs can be given for a tonic clonic or tonic seizure
sodium valproate | lamotrigine for female of child bearing potential
56
what drugs can be given for an absence seizure
sodium valproate | ethosuximide for females of child bearing potential
57
what drugs are given for encephalitis
IV acyclovir | IV benzylpenicilin
58
what is given for an ischaemic stroke
aspirin/clopidogrel | IV alteplase if <4.5 hours of symptoms beginning
59
what is given for ALS
riluzole
60
what is given for herpes zoster
acyclovir
61
meningitis usually in pregnant women
listeria
62
feeling of curtain coming down over eyes
amaurosis fugax
63
inheritance pattern of Duchenne muscular dystrophy
x linked recessive
64
roots affected in carpal tunnel syndrome
C6, 7, 8 and T1