haem

Question 1

what type of anaemia is iron deficiency

Answer 1

microcytic

Question 2

key symptoms of iron deficiency anaemia

Answer 2

brittle hair and nails
atrophic glossitis
angular stomatitis

Question 3

what type of cells are seen in iron deficiency anaemia

Answer 3

hypochromic

Question 4

side effect of treatment for iron deficiency anaemia

Answer 4

black stools

Question 5

what type of anaemia is B12 deficiency/pernicious anaemia

Answer 5

macrocyctic

Question 6

what type of anaemia is folate deficiency

Answer 6

macrocytic

Question 7

what type of anaemia is haemolytic anaemia

Answer 7

normocytic

Question 8

what is seen in haemolytic anaemia

Answer 8

increased reticulocytes

decreased spherocytes

Question 9

when does alpha thalassaemia present

Answer 9

in utero

Question 10

when does beta thalassaemia present

Answer 10

infancy

Question 11

what mutation causes polycythemia vera

Answer 11

JAK-2

Question 12

treatment for DIC

Answer 12

fresh frozen plasma

cyroprecipate if cardiac involvement

Question 13

causes of TTP

Answer 13

ADAMTS 13 mutation

Question 14

Usual age of ALL

Answer 14

child

Question 15

seen on aspirate in ALL

Answer 15

blast cells

Question 16

usual age of CLL

Answer 16

> 70

Question 17

cells seen in CLL

Answer 17

smudge

Question 18

treatment for AML

Answer 18

rituximab

Question 19

what is usually seen in AML

Answer 19

Auer rods

Question 20

Cause of CML

Answer 20

philadelphia chromosome t(9;22)

Question 21

treatment of CML

Answer 21

imantinib

Question 22

main cause of Hodgkin’s lymphoma

Answer 22

previous epstein-barr virus

Question 23

cells seen in Hodgkin’s lymphoma

Answer 23

Reed-Sternberg cells

Question 24

chemo used in Hodgkin’s lymphoma

Answer 24

ABVD

Question 25

symptoms of Hodgkin's lymphoma

Answer 25

painless rubbery lymph nodes worse when drinking alcohol

Question 26

Stage 1 of lymphoma

Answer 26

only 1 lymph node affected

Question 27

stage 2 of lymphoma

Answer 27

2 lymph nodes affected on same side of the diaphragm

Question 28

stage 3 of lymphoma

Answer 28

multiple lymph nodes affected on different sides of the diaphragm

Question 29

stage 4 of lymphoma

Answer 29

organs are affected as well as lymph nodes

Question 30

difference between stage a and b for lymphoma staging

Answer 30

stage b includes systemic symptoms such as fever, night sweats and headaches

Question 31

multiple myeloma diagnosis indicator

Answer 31

``` OLD CRAB > 65 hypercalcaemia renal disease anaemia bone pain ```

Question 32

proteins found multiple myeloma

Answer 32

Bence Jones

Question 33

What type of inheritance is Von Willebrand disease

Answer 33

autosomal dominant

Question 34

what type of cells are affected in myeloma

Answer 34

plasma

Question 35

what is felty's syndrome

Answer 35

rheumatoid arthritis neutropenia splenomegaly

Question 36

investigation for felty's syndrome

Answer 36

abdominal ultrasound scan

Question 37

2 species of protozoa that can cause malaria relapse

Answer 37

p. ovale | p. vivax

Question 38

chromosome abnormality seen with multiple myeloma

Answer 38

t(11;14)

Question 39

what is a complication of CLL

Answer 39

Richters syndrome

Question 40

what is Richters syndrome

Answer 40

transformation of CLL to a more aggressive lymphoma

Question 41

factor affected in haemophilia A

Answer 41

factor VIII

Question 42

factor affected in haemophilia B

Answer 42

factor IX