GI

Question 1

2 pharmacological treatments for GORD

Answer 1

PPI

H2 receptor antagonist

Question 2

Medication for Mallory-Weiss tear/oesophageal varices

Answer 2

Terlipressin

Question 3

Peptic ulcer treatment for H.pylori

Answer 3

PPI
clarithromycin
amoxicillin

Question 4

3 pharmacological treatments for UC

Answer 4

sulfasalazine
prednisolone
azathioprine

Question 5

3 pharmacological treatments for Crohn’s

Answer 5

azathioprine
infliximab
prednisolone

Question 6

Antibodies usually found in Coeliac patients

Answer 6

IgA Ttg

anti-endomysial

Question 7

Where is UC located

Answer 7

colon

Question 8

Is UC or Crohn’s continuous

Answer 8

UC is continuous

Crohn’s has skip lesions

Question 9

What appearance does Crohn’s have?

Answer 9

cobblestone

Question 10

3 main symptoms of IBS

Answer 10

stomach pain worse after eating/relieved after defecating
bloating
change in bowel habit

Question 11

Causes of pancreatitis

Answer 11

IGETSMASHED
idiopathic
gallstones
ethanol
trauma
steroids
mumps
autoimmune
scorpion venom
hyperlipidaemia
ERCP
drugs

Question 12

test for detecting pancreatitis

Answer 12

amylase

Question 13

Metaplasia seen in Barrett’s oesophagus

Answer 13

stratified squamous to simple columnar

Question 14

What type of inheritance is FAP

Answer 14

autosomal dominant

Question 15

appendicitis pain

Answer 15

starts around the umbilicus and localises to the right iliac fossa –> McBurneys point

Question 16

where is mcburneys point

Answer 16

2/3rds from the umbilicus, 1/3 from the right anterior superior iliac spine

Question 17

gold standard investigation for appendicitis

Answer 17

CT

Question 18

How is hepatitis A spread

Answer 18

faecal-oral

Question 19

how is hepatitis B spread

Answer 19

blood or bodily fluids

Question 20

which hepatitis contains DNA

Answer 20

hep b

Question 21

treatment for hep B

Answer 21

pegylated interferon alpha

Question 22

which hepatitis can only consist in conjunction with another

Answer 22

D can only occur with B

Question 23

What is haemochromotosis

Answer 23

where body absorbs too much iron from food

Question 24

what type of inheritance is haemochromotosis

Answer 24

autosomal recessive

Question 25

what key feature is seen in haemochromotosis

Answer 25

bronzing of the skin

Question 26

treatment of haemochromotosis

Answer 26

desferroxamine

Question 27

inheritance of Wilsons disease

Answer 27

autosomal recessive

Question 28

what is Wilson's disease a build up of

Answer 28

copper

Question 29

key feature seen in Wilson's disease

Answer 29

Kayser-Fleischer rings | bronze ring around the cornea

Question 30

inheritance pattern of alpha 1 antitrypsin deficiency

Answer 30

autosomal recessive

Question 31

2 organs involved A1AD

Answer 31

liver and lungs

Question 32

biggest cause of obstruction in the small bowel

Answer 32

adhesions

Question 33

biggest cause of obstruction in the colon

Answer 33

malignancy

Question 34

5 types of hernia

Answer 34

``` inguinal femoral umbilical incisional epigastric ```

Question 35

3 symptoms seen in cholangitis

Answer 35

RUQ pain fever jaundice

Question 36

5 main risk factors for gall stones

Answer 36

``` fat female forty family history fertile ```

Question 37

what sign is seen in ascending cholangitis

Answer 37

Murphys sign = severe pain on inhalation when pressing on RUQ

Question 38

what are the 2 signs seen in pancreatitis

Answer 38

cullens sign | grey turners sign

Question 39

what is cullens sign

Answer 39

umbilical bruising

Question 40

what is grey turners sign

Answer 40

flank bruising

Question 41

what do you give for a paracetamol overdose

Answer 41

N-acetylcysteine | activated charcoal

Question 42

what cells do PPIs act on

Answer 42

parietal

Question 43

what is 1st line investigation for a bowel obstruction

Answer 43

abdominal xray

Question 44

what antibodies are found in PBC

Answer 44

anti-mitochondrial antibodies

Question 45

does PBC or PSC affect woman more

Answer 45

PBC

Question 46

is PBC or PSC more strongly associated with IBD

Answer 46

PSC

Question 47

is PBC or PSC associated with an increased risk of colon cancer

Answer 47

PSC