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Phase 2a > GI > Flashcards

GI Flashcards

1
Q

2 pharmacological treatments for GORD

A

PPI

H2 receptor antagonist

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2
Q

Medication for Mallory-Weiss tear/oesophageal varices

A

Terlipressin

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3
Q

Peptic ulcer treatment for H.pylori

A

PPI
clarithromycin
amoxicillin

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4
Q

3 pharmacological treatments for UC

A

sulfasalazine
prednisolone
azathioprine

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5
Q

3 pharmacological treatments for Crohn’s

A

azathioprine
infliximab
prednisolone

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6
Q

Antibodies usually found in Coeliac patients

A

IgA Ttg

anti-endomysial

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7
Q

Where is UC located

A

colon

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8
Q

Is UC or Crohn’s continuous

A

UC is continuous

Crohn’s has skip lesions

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9
Q

What appearance does Crohn’s have?

A

cobblestone

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10
Q

3 main symptoms of IBS

A

stomach pain worse after eating/relieved after defecating
bloating
change in bowel habit

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11
Q

Causes of pancreatitis

A 
IGETSMASHED
idiopathic
gallstones
ethanol
trauma
steroids
mumps
autoimmune
scorpion venom
hyperlipidaemia
ERCP
drugs
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12
Q

test for detecting pancreatitis

A

amylase

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13
Q

Metaplasia seen in Barrett’s oesophagus

A

stratified squamous to simple columnar

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14
Q

What type of inheritance is FAP

A

autosomal dominant

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15
Q

appendicitis pain

A

starts around the umbilicus and localises to the right iliac fossa –> McBurneys point

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16
Q

where is mcburneys point

A

2/3rds from the umbilicus, 1/3 from the right anterior superior iliac spine

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17
Q

gold standard investigation for appendicitis

A

CT

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18
Q

How is hepatitis A spread

A

faecal-oral

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19
Q

how is hepatitis B spread

A

blood or bodily fluids

20
Q

which hepatitis contains DNA

A

hep b

21
Q

treatment for hep B

A

pegylated interferon alpha

22
Q

which hepatitis can only consist in conjunction with another

A

D can only occur with B

23
Q

What is haemochromotosis

A

where body absorbs too much iron from food

24
Q

what type of inheritance is haemochromotosis

A

autosomal recessive

25
Q

what key feature is seen in haemochromotosis

A

bronzing of the skin

26
Q

treatment of haemochromotosis

A

desferroxamine

27
Q

inheritance of Wilsons disease

A

autosomal recessive

28
Q

what is Wilson’s disease a build up of

A

copper

29
Q

key feature seen in Wilson’s disease

A

Kayser-Fleischer rings

bronze ring around the cornea

30
Q

inheritance pattern of alpha 1 antitrypsin deficiency

A

autosomal recessive

31
Q

2 organs involved A1AD

A

liver and lungs

32
Q

biggest cause of obstruction in the small bowel

A

adhesions

33
Q

biggest cause of obstruction in the colon

A

malignancy

34
Q

5 types of hernia

A 
inguinal
femoral
umbilical
incisional
epigastric
35
Q

3 symptoms seen in cholangitis

A

RUQ pain
fever
jaundice

36
Q

5 main risk factors for gall stones

A 
fat 
female
forty
family history 
fertile
37
Q

what sign is seen in ascending cholangitis

A

Murphys sign = severe pain on inhalation when pressing on RUQ

38
Q

what are the 2 signs seen in pancreatitis

A

cullens sign

grey turners sign

39
Q

what is cullens sign

A

umbilical bruising

40
Q

what is grey turners sign

A

flank bruising

41
Q

what do you give for a paracetamol overdose

A

N-acetylcysteine

activated charcoal

42
Q

what cells do PPIs act on

A

parietal

43
Q

what is 1st line investigation for a bowel obstruction

A

abdominal xray

44
Q

what antibodies are found in PBC

A

anti-mitochondrial antibodies

45
Q

does PBC or PSC affect woman more

A

PBC

46
Q

is PBC or PSC more strongly associated with IBD

A

PSC

47
Q

is PBC or PSC associated with an increased risk of colon cancer

A

PSC

Phase 2a (8 decks)

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