nervous tissue Flashcards

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1
Q

what is a nerve cell?

A

collection of neurons - responsible for generating and transmitting electrical signals
.type of nerve cell- neuroglia ( glial cells ) - cells that play essential supporting roles in nerve cell function

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2
Q

what are the 3 main components of a neuron?

A

. dendrites
. cell body ( nucleus )
. axon

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3
Q

what is the function of dendrites ?

A

. receives incoming electrical signals from nerve cell or environment .
. branches on dendrites ( arborizations ) vary from one dendrite to other they can be simple or elaborate- increase surface area

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4
Q

what is the function of cell body ( soma ) ?

A

. main site of metabolic support for a neuron
. most protein synthesis occurs in the cell body
-Sums electrical signals coming from dendrites

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5
Q

what is the function of axon ?

A

. this is where electrical signals leave the cell body

. axons end in terminal arborizations where neuron contacts other nerve cell or muscle cell

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6
Q

what is the point of contact where axon terminals contacts other nerve cell or muscle cell ?

A

. synapse

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7
Q

what are the four basic morphological types of nerve cells?

A
  1. anaxonic - no axon e.g retinal amacrine cell
  2. unipolar - one neurite emanating from the cell body
    e. g. sensory neurons
  3. bipolar - one dendritic process and one axon leave cell body
    e. g. retina
  4. multipolar - multiple neurite emanating from the cell body
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8
Q

what is the size of soma ?

A

10-25um

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9
Q

what are the stringy bits you can see in the soma ?

A

axon + dendrites ( neurite )

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10
Q

what are CNS grey and white matter ?

A

grey - numerous cell bodies and few myelinated axon

white - few cell bodies and more myelinated axon - more myelin causing white appearance

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11
Q

what are the PNS and CNS glial cells ?

A

CNS - oligodendrocytes , astrocytes and ependymal cell, microglia
PNS - schwann cell , satellite cell and macrophage

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12
Q

function of schwann cell ?

A

. produce myelin in the PNS.
. can provide one neuron with myelin
. neuron can receive myelin from many schwann cell
. wrap itself around axon

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13
Q

function of oligodendrocytes ?

A

. produce myelin in the CNS
. can provide several neurons with myelin
. wrap itself around a neuron

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14
Q

function of astrocytes ?

A
. important for blood:brain barrier
.have a role in damage repair
. store nutrients(glucose)
.astrocytes replicate - main source of CNS tumours
.isolate synapes
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15
Q

function of ependymal cells ?

A

line the ventricles of brain and central canal of spinal cord
involved in secretion of CSF

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16
Q

function of microglia ?

A
.normally 'dormant' 
. involved in CNS injury/inflammation
.move to damage site
.phagocytose pathogens
.release cytokines to attract other immune cells
17
Q

what are nerve cells ?

A

. they are collection of neurons.

. nerve cells can be sensory , motor or both

18
Q

what do sensory and motor neurons innervate within the eye ?

A

motor neurons - innervate muscles and glands

sensory neurons - optic nerve which takes messages from the retina to brain

19
Q

describe the structure of nerves?

A

. divided into bundles of neurons ( fasicles ) by connective tissue
.connective tissue between individual neurons (endoneurium)
. perineurium surrounds each bundle of neurons
. epineurium encloses the whole cell

20
Q

what are the functional consequences of the variation of diameter in axon ?

A

Larger diameter axons have a higher conduction velocity, which means they are able to send electrical signals faster.

21
Q

What is the diameter of axons?

What is the length of axon?

A

1um
up to 20um
in giant squid axons- 1mm
Length- 1mm-1m

22
Q

What is neuroglia?

A

supporting cells of the nervous system

23
Q

What are the functions of various classes of glial cell?

A
  • is to provide different forms of mechanicals, biochemical and physiological support for different parts of the neuron.
  • glial cells do not generate electrical impulses.
24
Q

How does myleination provided by 2 cell types differ?

A

A single oligodendrocyte provides myelin to several neurons
A single schwann cell provides myelin to one single neuron- however one single neuron can recieve its myelin from several different schwann cells.

25
Q

Which glial cells line the cerebral ventricles and why?

A

Ependyml cells- secrete the cerebrospinal fluid

26
Q

What are the dark areas between the fasciles?

A

blood vessels

27
Q

What are the vast majoirity of CNS neruons?

A

Multipolar

28
Q

What is the best example of bipolar neruon?

A

retina

29
Q

Where does unipolarity occur?

A

only exist in some sensory neurons of the PNS

-not in the eye

30
Q

What is the ventral horn of the spinal cord stained with?

A

holmes silver stain (Red.brown)
triple stain (blue)
-shows the grey matter- mostly filled with cell bodies
-the stains help identify the cells bodies of multipolar neurones.

31
Q

What does the cell body appear as in the spinal cord?

A

in the grey matter- which in the spinal cord is the darker area in the middle- that appears like the letter H

32
Q

What is the orbital nerve- which shows cross sections of cranial nerves stained with?

A

toludine blue.
These are a part of the CNS and innervate specific ocular structures.
In this section axons have a circular profile.