Nervous system - Dr. Roecker Flashcards
Cerebral ischemia results in infarction (necrosis) of brain tissue, death or disabled
Stroke
Rupture of saccular aneurysm.
Subarachnoid hemorrhage
Autoimmune demyelinating disease, very common, relapsing-remitting of neurologic deficits, white matter plaques (sclerosis) in brain and cord (multiple), young adult females, accumulation of neurological deficits: ataxia, diplopia, spasticity, bowel/bladder dysfunction.
Multiple sclerosis
Loss of spinal cord lower motor neurons, mixed upper and lower motor neuron damage, muscle atrophy, hyperreflexia, rapid progression, spares eyes muscles (Stephen Hawkins), usually death is rapid due to respiratory paralysis.
Amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis aka?
Lou Gehrig disease
MC cause of dementia in elderly, idiopathic, cortical atrophy, beta-amyloid plaque and Tau protein deposition, Neurofibrillary tangles, profound disability (lethal)
Alzheimer disease
Damage to dopaminergic neurons of substantial nigra, Lewy body inclusions, “pill rolling” tumor, rigidity, badykinesia (slow movement), loss of facial expression, immobility within 10 years.
Parkinson’s disease
Bilateral vestibular schwanommas (MRI), vision or hearing problems
Neurofibromatosis type II
Autosomal dominant, progressive, and wide spread cerebral degeneration, caudate nucleus atrophy, hydrocephalus ex vacuo, chorea, sever dementia, lethal w/in 15 years
Huntington disease
General term for demyelination due to Schwann cell or myelin cell damage.
Neuropathy.