Dr. Roecker's Rapid Review - Cardiovascular Pathology Flashcards
What is the name for plaques?
atheromas
What is hardening of the arteries called?
atherosclerosis
What cause hardening of the arteries?
atheromas (plaques)
Atherosclerosis has the greatest impact on which arteries?
Large muscular
Atherosclerosis ______ lumen.
narrows
Atherosclerosis increases what?
thrombosis
Atherosclerosis commonly follows what?
Damage to the endothelium (HTN)
Atheromas are filled with what? 3
Macrophages,
Necrotic cellular debris,
Cholesterol esters (lipids)
Atheromas are covered by what?
A fibrous cap
Atheromas may ______ and cause _____.
Rupture
Massive thrombosis
What is a common cause of MI?
When atheromas rupture and cause a massive thrombosis.
95% of hypertension cases are __________.
Essential
What is “essential hypertension”?
Idiopathic, familial history
VSD - Ventricular Septal Defect has a hole between what?
Left and right ventricles
What is the most common congenital defect?
VSD - Ventricular Septal Defect
Which defect has a hole between the left and right atria?
Atrial Septal Defect - ASD
ASD has a patent _____.
Foremen ovale
What is the most common cause of cyanosis at birth?
Tetralogy of Fallot
What four things make up Tetralogy of Fallot?
Large VSD
Aorta overriding VSD
Right ventricular outflow obstruction
Right ventricular hypertrophy
What 5 things do you see with coarctation of the aorta?
Narrowing of aortic arch, Upper extremity HTN, Lower extremity claudication (vascular), Cyanosis, Weak pulses
A localized malformation characterized by deformity of the aortic media, causing narrowing, usually severe, of the lumen of the vessel.
Coarctation of the aorta
What is transposition of the great vessels?
Reversal of the aorta and pulmonary arteries
Transposition of the great vessels causes?
Cyanosis
What is the most common cause of pleural effusion?
Congestive Heart Failure - CHF
Pleural effusion has no _______ and is _______.
No inflammation,
transudate.
Congestive Heart failure is the result of what? 3
Dysfunctional systole, diastole, or valvular dysfunction.
Valvular dysfunction in CHF could either be ____ or ____.
Stenosis
prolapse
Ventricular hypertrophy is most common on which ventricle?
left
Which type of hypertrophy is pathologic?
concentric
Which type of hypertrophy is the result of endurance training (athlete’s heart)?
eccentric
What is “heart muscle disease” called?
cardiomyopathy
What is the MC cardiomyopathy?
Dilated cardiomyopathy
Dilated cardiomyopathy is?
Dilation of all chambers
What causes dilated cardiomyopathy?
Alcohol, genetics, heart failure
Which cardiomyopathy has contractile gene mutations?
hypertrophic cardiomyopathy
In hypertrophic cardiomyopathy, the muscle is ________.
hypercontractile
Which type of cardiomyopathy has diastole dysfunction?
Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy may cause______ via _____.
Sudden death
Lethal arrhythmia
Which type of cardiomyopathy is rare?
Restrictive cardiomyopathy.
Which type of cardiomyopathy causes a stiff myocardium?
Restrictive cardiomyopathy.
What can cause restrictive cardiomyopathy? 3
amyloidosis (elderly)
Nutritional deficiency
helminths infection
Myocardial infarction (MI) causes ______, death of ________ aka ______ due to _______.
Heart attack,
Cardiac myocytes
Infarction
Ischemia
Females present with ____ MI symptoms in ______.
Mild
stomach
MI symptoms are:
Dyspnea,
Neck, jaw, or left arm pain
Death via MI is frequently the result of ________ (___) produced by electrical instability after myocyte necrosis.
Cardiac arrhythmias
V-fib
This causes sharp, substernal chest pain, reported as “crushing” or “pressure” worse with activity.
angina
Angina has at least ____% occlusion of which artery?
70
coronary
Angina is not and MI but associated with what?
Acute thrombosis of a coronary artery or vasospasm
What is angina that is becoming more intense and more frequent (pre-MI)?
Unstable angina
What is it called when pericardial sac becomes inflamed?
pericarditis
Pericarditis may cause what?
fibrinoid necrosis
Pericarditis may follow what two things?
MI
Viral infection
Right sided heart failure resulting from pulmonary pathology is called?
Cor pulmonale
What two pulmonary pathology cause Cor pulmonale?
Pulmonary HTN
pulmonary interstitial fibrosis
What is vasoconstriction of the hands, pallor, cyanosis (red, white, blue), benign and may be secondary to atherosclerosis?
Reynard’s phenomenon
What is the MC vasculitis in the elderly?
Temporal arteritis
Temporal arteritis is aka?
Giant cell arteritis
What are symptoms and signs of temporal arteritis?
Vision loss, headaches, fever
What region does the temporal arteritis affect?
Temporal region
What is the cause of temporal arteritis (aka giant cell arthritis)
idiopathic
Polyarteritis nodosa is inflammation of which arteries?
Small arteries (heart, renal)
Polyarteritis nodosa avoided which vessels?
Pulmonary vessels
What is the cause of Polyarteritis nodosa?
idiopathic
What happens if Polyarteritis nodosa goes untreated?
It is fatal
What is the most common vasculitis among children?
Kawasaki disease
Kawasaki disease attacks which artery and causes what in children?
Coronary arteries
Heart attacks
What is a sign of Kawasaki disease in children?
Strawberry tongue
Is Kawasaki disease common? What causes it?
No, rare
idiopathic
What is thromboangiitis obliterans aka?
Buerger disease
What is thromboangiitis obliterans (Buerger disease)?
Inflammation of the medium sized arteries of the hands and feet.
Buerger disease has a strong association with what?
Cigarette smoking
Buerger disease may cause what?
Ulceration and gangrene that require amputation