Nervous 1 Flashcards

1
Q

what is a ganglion?

A

a centralized group of electrically active cells

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2
Q

what is a brain?

A

a centralized command over the entire body, two lobes, more interneurons than direct primary neurons

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3
Q

when does a ganglion become a brain?

A

when there are two lobes, if it has more interneurons than primary ones, and if it has centralized command

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4
Q

what is the neocortex?

A

part of the cerebral cortex, highly organized and complex, has 6 layers

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5
Q

does having more neurons mean you’re smarter?

A

NO! whales have very complex neocortex, birds don’t have one but are very smart

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6
Q

frontal lobe is for

A

motor cortex, planning, long term memories, higher functions

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7
Q

temporal lobe is for

A

auditory cortex, memory formation, communication, facial recognition

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8
Q

pareital lobe does what

A

sensory integration from multiple modalities (somatosensory cortex)

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9
Q

what cations and anions do neurons use?

A

Na+, K+, Ca2+, Cl- and other anions

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10
Q

resting membrane potential is around

A

-60-70 mV due to a negative charge built up on the interior of the neuron

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11
Q

ions always want to flow _____ to eliminate electrical potentials.

A

down concentration gradients

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12
Q

resting membrane potential is maintained by _____

A

ion pumps, sodium potassium pumps

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13
Q

maintaining resting membrane potential is ______

A

an energy intensive process, 1 ATP per 3 Na+ ions

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14
Q

what are the two types of passive transport channels?

A

ligand-gated channels and voltage-gated channels

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15
Q

voltage gated sodium channels open at _____ and inactivate at

A

-50 to -55 mV

over 0

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16
Q

voltage-gated potassium channels open at and inactivate at

17
Q

action potentials are initiated at the

A

axon hillock

18
Q

rate of propagation is determined by

A

axon diameter: larger diameter means faster impulse

presence of myelin sheath: myelin means faster

19
Q

what are the two mechanisms of propagation?

A

continuous (unmyelinated) and saltatory (myelinated)

20
Q

what is the threshold level for an action potential?

21
Q

what is a graded potential?

A

small fluctuations in membrane potential due to the opening of ion channels

22
Q

depolarization has ___ potential and hyperpolarization has ____ potential

A

excitatory

inhibitory

23
Q

ionotropic receptors are ______. when the receptor is activated, the ion channel ____. can be either _____ or ____. they signal ____

A

ligand-gated ion channels

opens

excitatory

inhibitory

quickly

24
Q

metabotropic receptors are often _____. this signaling ____ and this is a _____

A

linked to an ion channel via signaling cascade

persists longer

G coupled protein receptor

25
\_\_\_\_\_\_ is the most abundant neurotransmitter, with it present in about 80% of all synapses in the brain.
glutamate
26
\_\_\_\_\_ is the brain's major inhibitory receptor.
GABA
27
\_\_\_\_\_\_ is the spinal cord's major inhibitory neurotransmitter
glycine
28
what is epilepsy?
a chronic seizure disorder with recurrent unprovoked seizures
29
what is a seizure?
the clinical manifestation of an abnormal and excessive excitation and synchronization of neurons
30
what are the two types of epilepsy in animals?
idiopathic and symptomatic
31
what are the causes of symptomatic epilepsy?
head injury, CNS infection, stroke, tumour, hypoglycemia, heat exhaustion, fever, parasites, poisoning
32
seizures are induced by \_\_\_\_\_\_. this is caused by \_\_\_\_
hyperexcitability of neuronal networks loss of balance between excitation and inhibition such as ion concentration mess up, ion channel function mess up, structural changes in synapses
33
how do you treat epilepsy?
by decreasing excitabiity or increasing inhibition
34