Nephrology Flashcards
Why are patients with Chron’s disease prone to getting kidney stones?
Patients with IBD and Crohn’s disease suffer fro mintestinal malabsorption- especially of fatty acids and bile salts.
Free calcium in the intestinal lumen is bound to the fatty acids and, therefore, is not absorbed into the body. This leads to a relative increase in oxalate absorption when compared to calcium. The increased oxalate will then need to be excreted within the urinary system.
As urinary oxalate excretion increases, so does the risk of calcium oxalate stone formation.
What is the mechanism of stone formation in a patient with IBD and chronic diarrhea with metabolic acidosis?
Decreased excretion of urinary citrate is associated with stone formation in patients with metabolic acidosis and chronic diarrhea.
Urinary citrate is a strong inhibior of stone formation.
What is the most comon complication of nephrotic syndrome?
The most likely complication of nephrotic syndrome is
venous thrombosis.
Other complications include: protein malnutrition, hypovolemia, acute kidney injury, and infection (the leading cause of death in nephrotic syndrome)
recurrent episodes of macroscopic hematuria usually within 5 days of a URI
IgA nephropathy
