Neoplastic Disorders (week 10) Flashcards

1
Q

neoplastic disease

A

includes many different diseases that occur due to accumulation of genetic changes due to heredity, environment, and behavior

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2
Q

what is a tumor

A

overgrowth of tissue independent to the controls that govern cell division and serves no use to the body

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3
Q

neoplasm

A

new tumor growth

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4
Q

what does cancer refer to

A

malignant tumor (aggressively expands and metastasizing)

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5
Q

characteristics of benign tumors

A
slow growers
not invasive to other tissues
encapsulated
cells do not divide rapidly
do not metastasize
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6
Q

characteristics of malignant tumors

A
grow rapidly
no encapsulation
rapid cell division
metastasize
invasive to local tissue
cross basement membranes
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7
Q

basement membrane

A

connective tissue structure that holds cells together, usually for a particular organ

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8
Q

carcinogenesis

A

initiation of cancer

multistage process

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9
Q

4 stages of carcinogenesis

A

initiation
promotion
transformation
progression

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10
Q

initiation

A

cell undergoes irreversible mutation

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11
Q

promotion

A

mutated cell divides and produces a tumor

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12
Q

transformation

A

mutated cells become cancerous (cells break off and metastasize)

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13
Q

progression

A

cell proliferation and tumor invasion into tissues

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14
Q

carcinoma

A

arising from epithelial tissue

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15
Q

adenocarcinoma

A

arising from ductal or glandular tissue

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16
Q

sarcoma

A

arising from connective tissue

17
Q

lymphoma

A

arising from lymphatic tissue

18
Q

leukemia

A

arising from blood forming tissue (marrow)

19
Q

normal characteristics of cells

A
contact inhibition
anchorage dependent
limited life span
differentiation
glycoprotein markers on membrane
20
Q

contact inhibition

A

cell division stops when dividing cells come into contact with other cells

21
Q

anchorage dependent

A

cells remain attached to basement membrane

22
Q

differentiation

A

specific purpose of cell