Neoplastic bone disease

Question 1

Tumour-like conditions

Answer 1

Fibrous dysplasia
Metaphyseal fibrous cortical defect/non-ossifying fibroma
Reparative giant cell granuloma
Ossifying fibroma
Simple bone cyst

Question 2

Benign bone tumours

Cartilagenous differentiation

Answer 2

Osteochondroma

Enchodroma

Chondroblastoma

Question 3

Benign bone tumours

Bone forming

Answer 3

Osteoid osteoma

Osteoblastoma

Osteoma

Question 4

Borderline malignancy

Answer 4

Giant cell tumour

Question 5

Malignant bone tumours

Answer 5

secondary mets

Primary:
Osteosarcoma
Chondrosarcoma
Ewing’s sarcoma

Question 6

Ollier’s syndrome

Answer 6

Multiple enchodromas

Question 7

Maffuci’s syndrome

Answer 7

Multiple enchodromas + haemangiomas

Question 8

Gardner syndorme

Answer 8

GI polyps + multiple osteomas + epidermoid cysts

Question 9

Radiolucent nidus with sclerotic rim

Answer 9

Osteoid osteoma

Question 10

Cotton wool calcification, O ring sign

Answer 10

Enchodroma

Question 11

Speckled mineralisation

Answer 11

Osteoblastoma

Question 12

Chinese letters

Answer 12

Fibrous dyslplasia

Question 13

Well defined bony protuberance

Answer 13

Osteochondroma

Question 14

Diaphyseal atlases/hereditary multiple exostoses =

Answer 14

multiple exostoses + short stature + bone deformities

Question 15

Soap bubble osteolysis

Answer 15

Fibrous dysplasia

Question 16

Shepherds crook deformity

Answer 16

Fibrous dysplasia

Question 17

McCune Albright

Answer 17

polyostotic dysplasia + cafe au lait spots + precocious puberty

Question 18

Simple bone cyst

Answer 18

Humerus/femur
Fluid filled unilocular
Lytic well defined

Question 19

Cartilage capped bony outgrowth

Answer 19

Osteochondroma

Question 20

Bone replaced by fibrous tissue

Answer 20

Fibrous dysplasia

Question 21

Bony outgrowth attached to normal bone

Answer 21

Osteoma

Question 22

Small benign bone forming lesion, night pain relieved by aspirin

Answer 22

Osteoid osteoma

Question 23

Elevated periosteum (Codman's triangle)
Sunburst appearance

Answer 23

Osteosarcoma

Question 24

Malignant mesenchymal cells

ALP +ve

Answer 24

Osteosarcoma

Question 25

Knee (60%) | Adolescence

Answer 25

Osteosarcoma

Question 26

Lytic lesion with fluffy calcification | Axial skeleton

Answer 26

Chondrosarcoma

Question 27

Malignant chondrocytes

Answer 27

Chondrosarcoma

Question 28

Axial skeleton Femur/tibia/pelvis >40yrs

Answer 28

Chondrosarcoma

Question 29

Onion skinning of periosteum

Answer 29

Ewing's

Question 30

Sheets of small round cells CD99+ve T11:22

Answer 30

Ewing's

Question 31

Long bone, pelvis <20yrs

Answer 31

Ewing's

Question 32

Lytic/lucent lesions right up to articular surface

Answer 32

Giant cell

Question 33

Osteoclast type multinucleate giant cells on background of spindle/ovoid cells

Answer 33

Giant cell

Question 34

Knee-epiphysis | 20-40yrs

Answer 34

Giant cell