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Pathology (AR) > Neoplastic bone disease > Flashcards

Neoplastic bone disease Flashcards

1
Q

Tumour-like conditions

A 
Fibrous dysplasia
Metaphyseal fibrous cortical defect/non-ossifying fibroma
Reparative giant cell granuloma
Ossifying fibroma
Simple bone cyst
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2
Q

Benign bone tumours

Cartilagenous differentiation

A

Osteochondroma

Enchodroma

Chondroblastoma

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3
Q

Benign bone tumours

Bone forming

A

Osteoid osteoma

Osteoblastoma

Osteoma

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4
Q

Borderline malignancy

A

Giant cell tumour

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5
Q

Malignant bone tumours

A

secondary mets

Primary:
Osteosarcoma
Chondrosarcoma
Ewing’s sarcoma

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6
Q

Ollier’s syndrome

A

Multiple enchodromas

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7
Q

Maffuci’s syndrome

A

Multiple enchodromas + haemangiomas

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8
Q

Gardner syndorme

A

GI polyps + multiple osteomas + epidermoid cysts

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9
Q

Radiolucent nidus with sclerotic rim

A

Osteoid osteoma

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10
Q

Cotton wool calcification, O ring sign

A

Enchodroma

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11
Q

Speckled mineralisation

A

Osteoblastoma

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12
Q

Chinese letters

A

Fibrous dyslplasia

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13
Q

Well defined bony protuberance

A

Osteochondroma

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14
Q

Diaphyseal atlases/hereditary multiple exostoses =

A

multiple exostoses + short stature + bone deformities

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15
Q

Soap bubble osteolysis

A

Fibrous dysplasia

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16
Q

Shepherds crook deformity

A

Fibrous dysplasia

17
Q

McCune Albright

A

polyostotic dysplasia + cafe au lait spots + precocious puberty

18
Q

Simple bone cyst

A

Humerus/femur
Fluid filled unilocular
Lytic well defined

19
Q

Cartilage capped bony outgrowth

A

Osteochondroma

20
Q

Bone replaced by fibrous tissue

A

Fibrous dysplasia

21
Q

Bony outgrowth attached to normal bone

A

Osteoma

22
Q

Small benign bone forming lesion, night pain relieved by aspirin

A

Osteoid osteoma

23
Q 
Elevated periosteum (Codman's triangle)
Sunburst appearance
A

Osteosarcoma

24
Q

Malignant mesenchymal cells

ALP +ve

A

Osteosarcoma

25
Q

Knee (60%)

Adolescence

A

Osteosarcoma

26
Q

Lytic lesion with fluffy calcification

Axial skeleton

A

Chondrosarcoma

27
Q

Malignant chondrocytes

A

Chondrosarcoma

28
Q

Axial skeleton
Femur/tibia/pelvis
>40yrs

A

Chondrosarcoma

29
Q

Onion skinning of periosteum

A

Ewing’s

30
Q

Sheets of small round cells
CD99+ve
T11:22

A

Ewing’s

31
Q

Long bone, pelvis

<20yrs

A

Ewing’s

32
Q

Lytic/lucent lesions right up to articular surface

A

Giant cell

33
Q

Osteoclast type multinucleate giant cells on background of spindle/ovoid cells

A

Giant cell

34
Q

Knee-epiphysis

20-40yrs

A

Giant cell

Pathology (AR) (25 decks)

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