Histo Flashcards

1
Q

Small cell cancer =

A

oat cell cancer

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2
Q

Sjogren’s

A

destruction of lacrimal and salivary glands leading to dry eyes and mouth

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3
Q

Heliotrope rash

A

dermatomyositis

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4
Q

Wilson’s gene

A

ATP7B

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5
Q

Aflatoxin –>

A

HCC

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6
Q

What kind of fibrosis do you see in PBC?

A

onion ring fibrosis

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7
Q

Pemphigoid

A

blisters don’t rupture easily

Nikolsky sign -ve

IgG to hemidesmosomes

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8
Q

Pemphigus

A

Nikolsky sign +ve]acantholysis

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9
Q

Green discharge seen in which breast problem?

A

duct ectasia

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10
Q

Area of calcification on mammogram

A

DCIS

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11
Q

artichoke like and similar to fibroadenoma

A

Phyloides tumour

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12
Q

Sign seen in giant cell tumour

A

Soap bubble

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13
Q

aortic regurg and cystic medial necrosis

A

Marfan’s

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14
Q

Stages of MI

6-24h

1-4d

5-10d

Months

A

Necrotic cell death

Infiltration of polymorphs

Removal of debris

Decellularising scar

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15
Q

Which zones do you get ischaemic colitis in

A

Watershed zones

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16
Q

HNPCC

A

cancers are poorly differentiated and highly aggressive

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17
Q

Keratin pearls

cell junctions

intercellular prickles

A

Lung SCC

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18
Q

Post acute MI –> pansystolic murmur

A

myomalacia corids

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19
Q

mid sytolic click and late systolic murmur

A

myxomatous mitral valve

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20
Q

Nepalese man, severe watery diarrhoea. Hypokalaemia and metab acidosis. RUQ mass, raised stool bicarb and -ve urine anion gap

A

VIPoma

Ass with MEN 1

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21
Q

Large cystic mass, presence of epithelium. Has an epithelial wall/capsule that contains fluid

A

Cystadenoma

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22
Q

Fluid filled collection contained within a well defined capsule of fibrous granulation tissue or a combo of both. does NOT possess epithelial lining

A

Pancreatic pseudocyst

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23
Q

Incomplete fusing of the pancreatic buds

A

Pancreas divisum

24
Q

Test for H.pylori

A

CLO test

URea

25
Q

Watery diarrhoea, abdo cramps, nausea, vomiting and low grade fever

A

cryptosporoidosis

26
Q

Steatorrhoea. Acid Schiff PAS +ve macropages

A

Whipple’s

Tropheryma Whipplei

27
Q

Sometimes ass with Hep B/C, can cause aneurysms.

p-ANCA

A

Polyarteritis nodosa

28
Q

Which amyloidosis do you see with amyloidosis

A

beta2 microglobulin

29
Q

Cobblestoning

A

Crohn’s

30
Q

Inverted loop of bowel

A

Sigmoid volvulus

31
Q

Acute/chronic bleeding and IDA

A

Angiodysplasia

32
Q

Cauliflower shaped adenoma

A

Villous adenoma

33
Q

Which artery to transtentorial hernias compromise

A

PCA

Occipital lobe infarct

34
Q

Blurred vision + vomiting

Upper anterior headache

A

Glaucoma

35
Q

Weakness in legs>arms post infarct

A

ACA infarct

36
Q

Raised TRH –>

A

galactorrhoea

37
Q

cystic dilatation of duct during lactation due to obstruction

A

galactocele

38
Q

Microcalcification. FNA = cells have pleomorphic nuclei and lump has necrotic centre

A

DCIS

39
Q

central nipple discharge. FNA = branching fibro vascular cores covered by cytologically bland epithelium

A

Duct papilloma

40
Q

Multifocal breast lumps

A

LCIS

41
Q

Multple bilateral masses

<10mm

FNA = turbid fluid

A

breast cyst

42
Q

MIC2 (CD99)

A

Ewing’s

43
Q

Bx = neutrophilic inflammatory infiltrate. Mottleed rarefaction and lifting of pereosteum

A

Osteomyelitis

44
Q

Urine calcium output in hypercalcaemia with raised PTH

A

1o HPTH: high urine calcium output

FHH: low calcium output

45
Q

Commonest bony tumour, around knee and painless and slow growing

Maybe prev #

A

osteochondroma

46
Q

Largest ovarian neoplasm

A

mucinous tumour

47
Q

germ cells mixed with lymphs

A

dysgerminoma

48
Q

fibrous tissue containing spindle cells and lipid

A

Thecoma

49
Q

squamous epithelium mixed with intestinal epithelium

A

mature cystic teratoma

50
Q

malignant cells surrounded by serous fluid and psamomma bodies

A

serous cystadenoma

51
Q

Seminoma

A

Radiosensitive, 4th decade

52
Q

100% PPV for malignant cytopathological Dx

A

FNA

53
Q

Palpable breast lump in clinical setting

A

FNA

54
Q

OVarian cyst

A

FNA

55
Q

PCP Dx

A

Fluid cytology of alveolar washings

56
Q

Impalpable breast lump

A

stereotactic radiographic cytological sampling method