Neonatology Flashcards

1
Q

What are the components of the ToRCHH screen

A
Toxoplasmosis
Rubella
CMV
HIV
HSV
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2
Q

Risk factors for hypoglycaemic neonate

A
  • Diabetic mother
  • Haemolytic disease of the newborn
  • Preterm
  • Inborn errors of metabolism
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3
Q

Treatment for hypoglycaemic neonate

A

40% dextrose gel

usually self-revolving

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4
Q

What causes haemolytic disease of the newborn

A

Transplacental passage of maternal antibodies –> immune haemolysis of foetal RBC

Due to ABO incompatibility/ rhesus alloimmunisation

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5
Q

Presentation of haemolytic disease of the newborn

A

Hydrops foetalis,

Jaundice <24h

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6
Q

When does pathological jaundice occur in a newborn

A

Within first 24h

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7
Q

Explain why physiological jaundice occurs

A

Higher rate of RBC breakdown in neonates due to

  • shorter RBC lifespan
  • higher conc of RBC
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8
Q

Where does neonatal jaundice first occur

A

Face and forehead

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9
Q

What investigations should be done to identify cholestatic (obstructive jaundice in a child)

A

o USS
o Hepatobiliary iminodiacetic acid radionuclide scan
o Liver biopsy
o Laparotomy

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10
Q

When does breastmilk jaundice occur

A

3 days,
peaks by 5-15 days,
Resolves by 6 weeks (latest 4 months)

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11
Q

Conservative management of breast milk jaundice

A

Increase feeds

leads to increased bowel movements, increased excretion of bilirubin

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12
Q

What causes neonatal respiratory distress syndrome

A

Inadequate production of lung surfactant

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13
Q

What causes neonatal respiratory distress syndrome

A

Inadequate production of lung surfactant

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14
Q

How to reduce risk of neonatal respiratory distress syndrome

A

Antenatal corticosteroids

  • Accelerates foetal surfactant production
  • Accelerates lung maturation
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15
Q

Why is transient tachypnoea of the newborn common in babies from C section

A

Lung fluid doesnt get squeezed out like in vaginal birth

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16
Q

Does large or small airways obstruction occur first

A

Large airways

17
Q

Complications of large airway obstruction from meconium aspiration

A
  • reduced lung compliance
  • atelectasis
  • hypoxaemia
  • hypercapnea
  • respi acidosis
18
Q

Complications of small airway obstruction from meconium aspiration

A
  • Inflammation
  • pulmonary oedema
  • vaso and bronchoconstriction
  • collapse of airways
  • inactivation of surfactant
19
Q

What heart rate is concerning in neonatal sepsis

A

> 160bpm

20
Q

What respi rate is concerning in neonatal sepsis

A

> 60 breaths/min

21
Q

What O2 sats is concerning in neonatal sepsis

A

<90%

22
Q

What temperature is concerning in neonatal sepsis

A

> 38 or <36C

23
Q

Empirical antibiotics for neonates

A

IV benzylpenicillin +

Gentamycin

24
Q

Antibiotics for suspected meningitis in neonates

A

Empirical +
Ampicillin/ amoxicillin +
Cefotaxime

25
Q

Antenatal risk factors for hypoxic ischaemic encephalopathy in neonates

A
  • Maternal diabetes
  • Pre-eclampsia
  • Congenital infections
  • Cardiac disease
  • Placental insufficiency
  • Drug, alcohol abuse
  • Severe foetal anaemia
26
Q

Labour risk factors for hypoxic ischaemic encephalopathy in neonates

A
  • Excessive placental bleeding
  • Very low maternal BP
  • Umbilical cord accidents
  • Prolonged labour
  • Abnormal foetal position
  • Rupture of placenta/ uterus
  • Amniotic fluid embolism
27
Q

Postnatal risk factors for hypoxic ischaemic encephalopathy in neonates

A
  • Severe cardiac/ pulmonary disease
  • Infections
  • Severe prematurity
  • Low neonatal BP
  • Brain/ skull trauma
  • Congenital brain malformations
28
Q

What is given to all newborns to prevent haemolytic disease of the newborn

A

Vit K

29
Q

Components of the Apgar score

A
  • Appearance
  • Pulse (>100bpm is good)
  • Grimace
  • Activity (4 flexed limbs that resist extension)
  • Respiration