nematode Flashcards
nematode route of infection
ingested
ingested: enterobious, ascaris, toxocara, trichinella
You’ll get sick if you EATT these
enterobious
ascaris
toxocara
trichinella
Cutaneous nematode route of infection
strongyloides
ancylostoma
necator
These get into your feet from the SANd
Cutaneous nematode infection
strongyloides
ancylostoma
necator
Bites nematode routes of infection
Loa loa
ONchocerca volvulus
Wuchereria bancrofti
Lay LOW to avoid getting bitten
Loa loa
onchocerca volvulus
Wuchereria bancrofti
how does immune respone to helmints include
eosinophils
what type of hypersentiivity reaction in response to helmnitsh
eosinophils act by type I and Type II hypersentivity
neutraliziation of histamine and leukotries in response to helminths
Type I HSR
eosinophisl attach to surface of helminths via IgE and release cytotoxins (major basic protein) contained in granules
Type 2 HSR
cauess anal pruritius (diagnosed by seeing egg via tape test on perianal region
enterobius vermicularis (pinworm)
perianal itching
enterobius
transmission of enterobious
fecal oral
treatment of enterobious
pyrantel pamoate
bendazoles (albendazole=1st line)
obstruction at ileocela valve, biliary obstruction, intetisnal perforatino, migrates from nose/mouth
ascaris lumbricoides (giant roundworm)
fecal oral transmission; knobby coated oval eggs seen in feces under microscope
ascaris lumbricoides
vomiting, diarrhea, epigastric pain (may mimic peptic ulcer)
strongyloides stercoralis (threadworm)
larva currens seen in
strongyloides
what is larva currens
pruritic, erythemaouts linear streaks on thigh + buttocks
larvae in soil penetrate skin; rhabditiform larvae seen in feces under microscope
strongyloides
treatment for strongyloides
ivermectin
bendazoles
intestinal biopsy of strongyloides
eggs and adult parasites
SE asia: tropical and warm temperate regions
strongyloides
anemia by sucking blood from intestinal wall
ancylostoma duodenale, necator americanus (hookworms
Cutaneous larva migrans
pruritic, serpiginous rash from walking barefoot on contaminated beach
larvae penetrate skin
ancylostoma
walking barefoot on contaminted beach
cutaenous larva migrans
larvae enter bloodstream, encyst in striated muscle -> muscle inflimmation
trichinella spiralis
fever vomiting nausea perioriblal edema , myalgia in trichinella spiralis
trichinosis
transmission of trichinella
undercooked meat (esp pork) fecal oral : less likely
often asymptomatic; loose stools/aenmia, rectal prolapse in children (heavy infection)
trichuris trichiura (whipworm)
fecal oral transmission
trichuris trichiura
visceral larva migrans
toxocara canis
nematodes migrate to blood through intestinal wall -> inflammation and damage
visceral larva migrans
often affects heart (myocarditis), liver eyes(visual imparimetn blindness) and CNS (seizures, coma)
visceral larva migrans
transmission of toxocara
fecal oral
skin changes , loss of elastic fibers and river blindness (black flies, black skin nodules, black sight)
onchocerca volvulus
transmission of onchocerca volvusus
female blackfly
allergic reaction to microfilaria possible
onchocerca volvulus
swelling in skin, worm in conjunctiva
loa loa
transmision of loa loa
deer fly, horse fly, mango fly
elephantiasis
wuchereria bancrofti
elephantiasis transmission
female mosquito
anotehr name for elephantiasis
lympahtic filariasis
explain elephantiasis
worms invade lymph nodes :> inflammtion -> lymphedema
symptom onset after 9mo-1 yr
3 cestodes (tapeworm)
taenia solium
diphyllobothrium latum
echinococcus granulosus
intestinal tapeworm; ingestion of larvae encysted in undercooked pork
T. solium
cysticercosis, neurocysticercosis
Taenia solium
undercooked pork; seizures subcutaneous nodules , intramuscular calcificaitons
cysticercosis
transmission of cysticercoiss and neurocysticerocis
ingestion of eggs in food contaminated w human feces
vitamin B12 deficiency (tapeworm competes for B12 in intestine) -> megaolblastic anemia
Diphyllobothrium latum
transmission of d. latum
ingestion of larvae in raw freshwater fish
hydatid cysts (eggshel calcifciation) in liver
echinococccus granulosus
cyst rupture can cause anaphylaxis
e. granulosus
ingestion of eggs in food contamined with dog feces
echinococcus granulosus
sheep are an intermediate host
echinococcus granulosus
trematodes (flukes) include
Schistosoma, clonorchis sinensis
diagnosis of neurocysticerocisis
seizures
cysts on CT mri, eosinophilia, increase ESR