Neisseria Meningitidis Flashcards
1
Q
What infection can it cause?
A
Meningitis and Spesis
2
Q
What specific treatment is there?
A
Ceftriaxone
3
Q
What virulence factors does n. meningitidis have?
A
Pili for attachment
Endotoxin to stimulate inflammation
Polysaccharide capsule to promote adherence and prevent phagocytosis.
Multiple serogroups
4
Q
What is its microscopic appearance.
A
Gram Negative diplococci
5
Q
How do we prevent it in the UK?
A
Vaccination ACWY and B
6
Q
Where may it exist as a commensal?
A
Nasopharynx
7
Q
Mode of transmission
A
Aerosol
8
Q
Is meningitis a notifiable disease? why?
A
Yes- monitoring by PHE and close contacts considered for vaccination and prophylactic treatment.
