Neisseria Meningitidis Flashcards

1
Q

What infection can it cause?

A

Meningitis and Spesis

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2
Q

What specific treatment is there?

A

Ceftriaxone

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3
Q

What virulence factors does n. meningitidis have?

A

Pili for attachment
Endotoxin to stimulate inflammation
Polysaccharide capsule to promote adherence and prevent phagocytosis.
Multiple serogroups

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4
Q

What is its microscopic appearance.

A

Gram Negative diplococci

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5
Q

How do we prevent it in the UK?

A

Vaccination ACWY and B

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6
Q

Where may it exist as a commensal?

A

Nasopharynx

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7
Q

Mode of transmission

A

Aerosol

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8
Q

Is meningitis a notifiable disease? why?

A

Yes- monitoring by PHE and close contacts considered for vaccination and prophylactic treatment.

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