Adenovirus Flashcards
How can you detect adenovirus?
Antigen screening or Viral PCR
How do infants present with adenovirus?
Acute febrile pharyngitis
What organs can it effect?
Lots including eyes conductive and cornea
pharynx
GI tract
UTI
What are the symptoms?
Wide range of sites of infection so depends where is infected.
Cough/ sore throat/ nasal congestion and a fever suggest pharyngitis or RTI
Can you treat adenovirus?
With supportive treatment but not many antivirals
How would you catch an adenoviral gastroenteritis?
Food
How would you get a RTI from adenovirus?
Inhaled/ respiratory route transmission
What FBC measure would be high in adenovirus?
Lymphocytes
Describe the viral structure
Icosahedral non-enveloped double stranded DNA with structures that help receptor mediated endocytosis
What does adenovirus do in the cell?
Genome is uncoated and enters the nucleus.
Cell regulation proteins are inactivated.
Transcription of viral proteins is high
Cell dies and virus leaks out.
What supportive treatment can you offer?
Antipyeretics
Analgaesia
Hydration
