Escherichia Coli Flashcards
1
Q
Outline the mechanism of infection for E coli
A
Normal GI commensal
Faecal-oral transmission
Bacterial translocation (female UTI)
2
Q
What infections can E coli cause?
A
UTI Intestinal disease Neonatal meningitis Pneumonia Sepsis
3
Q
If a female presents with a UTI and you suspect E coli what would you prescribe?
A
Trimethoprim- inhibits folic acid synthesis
4
Q
Urine dipstick would show what in a UTI?
A
Increase nitrates and increase leukocyte esterase
5
Q
What cell would have an increased cell count?
A
neutrophils
6
Q
Who gets E coli infections?
A
Women- UTI
Older patients
Antimicrobial users
7
Q
Describe the gram stain.
A
gram negative bacili
8
Q
List E coli virulence factors
A
Pili Lipopolysaccharide cell wall- antigenic Endotoxins Catalase positive Oxidase negative Anaerobe
