Neisseria Flashcards
The only genus of Gram Negative cocci that frequently cause disease. Obligate human pathogens.
Neisseria
-> Gonorrhea, Bacterial meningitis and septicemia
Primary reservoir for N. meningitidis?
Human nasopharynx
Gonococci colonizes _____ in women or ____ in both sexes.
Cervix
Distal urethra
Gonococci:
- Shed thru:
- Flagella?
- Motile?
- Genital secretions
- No
- No
Gonococci spread and multiply by _____ microvilli engulfing the bacteria (internalization by _____ directed endocytosis). They multiply within ____ and then are discharged into subepithelial connective tissue.
Non-ciliated
Parasite
Vacuoles
Gonococci damage tissues not thru ______ but instead thru _____, causing sloughing of ____ cells and inflammation thru non-ciliated cell lysis.
Exotoxins
LPS
Ciliated
- Gonococcal infection of female upper reproductive tract (inflammation of uterus, tubes, infertility, ectopic pregnancy)
- Epididymitis (male infection)
Pelvic Inflammatory Disease (PID)
Truth: This is a horrendous lecture.
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