Neglected Diseases Flashcards

1
Q

What are Neglected Diseases?

A

diseases associated with significant morbidity and economic loss
-children most affected

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2
Q

What are some key neglected disease?

A
  • Schistomiasis
  • Onchoceriasis (river Blindness)
  • Lymphatic Filariasis (Elephaniasis)
  • Guinea Worm
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3
Q

Onchoceriasis is also known as?

A

River Blindness

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4
Q

What is the vector in River Blindness?

A

A fly

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5
Q

What are the symptoms of River Blindness?

A

Eye lesions that can eventually lead to blindness, and skin lesions (children often leading around their parents with a stick due to blindness).

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6
Q

What could eliminate the disease?

A

1 mg/kg of Mectizan once a year eliminates the Onchocerciasis disease!

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7
Q

What does Trachoma cause?

A

It causes blindness; disease of the eye, bacterium Chlamydia trachomatis (threatens to blind 10% of the population!)

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8
Q

Why is the Trachoma disease overlooked?

A

its hidden in communities with over crowded conditions, limited water.

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9
Q

How is Trachoma spread?

A

spread on infected person’s hands or clothing or may be carried by flies that have come in contact with discharge of the infected person’s nose or eyes.

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10
Q

Who is more likely to be blinded by Trachoma?

A

Women are 3x more likely to be blinded, blindness is slowly (takes years)

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11
Q

What is the second most tropical disease besides Malaria?

A

Schistosomiasis; disease caused by blood born fluke (lives in snails)

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12
Q

Where did Schistosomiasis originate?

A

In Africa; carried to South America with slave trade (Brazil, Caribbean)

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13
Q

What are the symptoms of Schistosomiasis?

A

-blood in urine, anemia, impaired growth, poor cognition, bladder cancer, kidney malfunction, liver and spleen complications.

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14
Q

What is the transmission cycle of Schistosomiasis?

A

Snail Host lays larvae in water, larvae swim in hair folicals of human swimming in water, human carries disease.

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15
Q

does Schistosomiasis exemplify the burden of disease?

A

Yes, only in low income countries.

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16
Q

Is the elimination of Guniea Worm possible?

A

Yes, 1985 Carter foundation started to try to eradicate the disease. Pakistan is free and India is almost there.

17
Q

How many cases are in Africa?

A

100s of cases in Africa

18
Q

What do Eradication characteristics included in the stop of Guniea Worm?

A
  • easily recognizable
  • seasonal
  • low transmissibilty
  • sound prevention (filters, clean water)
  • outbreaks easily contained
19
Q

Lymphatic Filariasis is also known as?

A

Elephantiasis

20
Q

Who is the vector for Lymphatic Filariasis?

A

A mosquito.

21
Q

What is the key to prevent infectious diseases?

A

POVERTY REDUCTION IS KEY