Chronic Diseases Flashcards
According to Epigenetics, what is determined in the first 1000 days of life?
Half of your lifetime health
What is Epigenetics?
A Stably inherited phenotype resulting from changes in a chromosome without alterations in the DNA sequence
In an Epigenetics study they fed one mouse a calorie-restricted diet and one mom mouse a normal diet, what were the results of this test?
The offspring of the calorie-restricted mother grew to be larger and had yellow fur compared to the normal sized/ brown mouse.
In the Epigenetics, what did scientists discover in the Dutch Famine Birth Cohort Study?
These pregnant mothers were under nutrition due to the DHW and as result at birth all the children had lower birth rates, higher neonatal mortality rates, higher rates of infection.
What are Chronic Diseases?
Ongoing illnesses or conditions that are generally not curable (eg heart disease, cancer, diabetes, arthritis)
How many people do Chronic Diseases affect?
Almost half of all Americans (133 million in 2005)
What accounts for 70% of all deaths?
Chronice Disease- it acconts for one-third of the years potential life lost before age 65
In 1900 what was the leading causes of death?
Pneumonia, influenza, TB, diarrhea
In 1925 what was the leading causes of death?
Heart disease, pneumonia, nephritis, cancer
In 1950 what was the leading causes of death?
Heart disease, cancer, stroke, accidents
In 2000 what was the leading causes of death?
Heart disease, cancer, stroke, COPD
In terms of worldwide, chronic disease are the leading cause of death in many countries but not in the poorest ones, how does this impact low and middle income countries?
Worldwide chronic disease was 60% of all deaths, but in low and middle impact countries chronic disease is the culprit for 80% of all deaths.
What percentage of women have not been adequately checked for cervical cancer?
80% of women
What are some links as to causes of increases of chronic disease in poorer countries?
- link with infectious diseases and infections
- reproductive health related cancers
- lack of prevention
- changes in lifestyle, finances, cultural norms
Is funding disproportionate for chronic disease in low and middle income countries?
Yes, the leading cause of death in these countries is Cancer, yet the most funding goes to HIV/AIDS and cancer’s funding is dead last.