NBSS (neuroscience) - Introduction to Stress and Mental Health Flashcards

1
Q

what are the two processes that become activated in stress?

A
  • sympathetic nervous system
  • hypothalamic pituitary adrenal HPA
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2
Q

what is the Autonomic nervous system made up of?

A

sympathetic “fight or flight”

parasympathetic “rest and digest”

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3
Q

what happens in the parasympathetic nervous system

A

acetyl choline released

calm and relaxed

decrease heart rate

decrease blood pressure

iris relaxes, small pupils

increase gut motility

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4
Q

what happens in the sympathetic nervous system

A

noradrenalin released

fight or flight

increase heart rate

increase blood pressure

iris contracts so pupil is larger

decrease gut motility

RELEASES CRF, ACTH AND CORTISOL!

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5
Q

what 5 areas of the brain are involved in the HPA axis?

A

amygdala
hypothalamus
pituitary gland
pre-frontal cortex
hippocampus

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6
Q

what is the difference between autonomic nervous system and HPA?

A

ANS promotes psychological changes, HPA is a hormonal system

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7
Q

what is the amygdala concerned with and what does it release?

A

concerned with emotion, motivation and fear

releases CRF (corticotropin-releasing factor)

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8
Q

what is the hypothalamus and pituitary involved with and what does it release

A

involved in control of emotional reactions, feeding, and drinking

releases ACTH (adrenocorticotropic hormone)

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9
Q

what is the hippocampus involved in?

A

organising memory storage in cortex and retrieving memories stored in cortex

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10
Q

what is the prefrontal cortex involved with

A

planning and organising behaviour based upon the use of working memory

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11
Q

these 5 areas of the brain involved in the HPA axis: amygdala
hypothalamus
pituitary gland
pre-frontal cortex
hippocampus
are all linked to what?

A

adrenal glands

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12
Q

where are the adrenal glands located

A

outside the brain

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13
Q

how do the adrenal glands communicate with the body?

A

adrenal cortext on outside of the gland releases cortisol directly to blood stream

it responds to ACTH released by the pituitary gland

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14
Q

what are 2 types of glucocorticoids

A

cortisol and corticosterone

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15
Q

what do glucocorticoids bind to?

A

GR receptors (glucocorticoid receptors) located on:

amygdala
hypothalamus
pituitary gland
pre-frontal cortex
hippocampus

^ The parts involved in the HPA axis

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16
Q

what is the HPA baseline

A

small amount of hormone cortisol is secreted continuously from adrenal cortex into blood, broken down by enzymes so levels remain low

17
Q

what happens in the HPA during acute stress?

A
18
Q

what happens in the HPA during chronic stress?

A
19
Q

when do changes occur in the HPA system

A

minutes after activation

20
Q

how is the HPA axis activated

A

release of corticotrophin-releasing hormone from paraventricular nucleus of hypothalamus

21
Q

what is DSM-5?

A