Naloxone

Question 1

Narcan (naloxone)

Class

Answer 1

Narcotic antagonist

Question 2

Narcan (naloxone)

Action

Answer 2

Displaces narcotics from opiate receptor sights.

Question 3

Narcan (naloxone)

Indication

Answer 3

Overdose of narcotics or their derivatives:
Heroin
Morphine
Methadone
Paregoric
Codeine
Oxycodone
Demerol
Darvon
Fentanyl (sublimaze)
Dilaudid (hydromorohone)
Talwin (pentazocine)
Lomotil (dipenoxylate)
Coma of unknown etiology

Question 4

Narcan (naloxone)

Dose/route

Answer 4

2mg IVP, use IN, IM, SL if IV cannot be started.

Titration for respiratory effect. MR q 3-5 min

Question 5

Narcan (naloxone)

Peds dose

Answer 5

0.1 mg/kg IVP, IO, IN; MR q 3-5 min 0-5yr or < 20kg

Question 6

Narcan (naloxone)

Onset

Answer 6

1-2 min IV, IO, IN; slightly longer IM.

Question 7

Narcan (naloxone)

Contra

Answer 7

Hypersensitivity to Narcan

Question 8

Narcan (naloxone)

Adverse effects

Answer 8

Withdrawal S/S with rapid reversal:
n/v
tachycardia
tachypnea
combative behavior
MI
return of chronic pain.

Question 9

Narcan (naloxone)

Precautions

Answer 9

1) Rapid reversal of narcotic OD may cause withdrawal S/S, titrate for adequate respirations.
2) Monitor EKG & VS
3) High potential for rapid relapse if duration of narcotic exceeds Narcan (monitor for re-administration).
4) Use w/ caution in newborns w/ suspected drug Hx exposure.

Question 10

Narcan (naloxone)

Supplied

Answer 10

2mg/ml preload or ampule