Dopamine

Question 1

Dopamine (intropin)

Class

Answer 1

Sympathomimetic

Question 2

Dopamine (intropin)

Action

Answer 2

• Stimulates dopaminergic, alpha and beta receptors of sympathetic NS.
• Low dose stimulates dopaminergic receptors (= renal and mesenteric).
• Mid dose stimulates beta receptors (= + inotrope effects).
• High dose stimulates alpha receptors (= peripheral renal and mesenteric vasoconstriction).

Question 3

Dopamine (intropin)

Indication

Answer 3

DOC for cardiogenic shock.
Bradycardia with hypotension.
Other shock states after fluid resuscitation.

Question 4

Dopamine (intropin)

Dose route

Answer 4

5-20 mcg/min IV infusion, dosage ranges:
5-10 mcg/kg/min dosage = beta stimulation.
Over 10 mcg/kg/min dosage = alpha stimulation.

Question 5

Dopamine (intropin)

Peds dose

Answer 5

2-15 mcg/kg/min IV infusion

Question 6

Dopamine (intropin)

Contra

Answer 6

Hypovolemia shock

Tachydysrhythmias

Question 7

Dopamine (intropin)

Adverse effects

Answer 7

CNS= h/a
CV= ventricular irritability, dysrhythmias, HTN (high dose), hypotension
GI=n/v

Question 8

Dopamine (intropin)

Precautions

Answer 8

Monitor V/S and EKG continuously!
Use supplemental O2
If unwanted rise in diastolic pressure is seen = stop infusion.
Tissue necrosis occurs on extravasion
Incompatible with bicarb

Question 9

Dopamine (intropin)

Supplied

Answer 9

400mg in 250 ml D5W (1600 mcg/ml) premix bag