Naloxone

Question 1

Naloxone - Contraindications

Precautions (2)

Answer 1

Contraindications:
Nil of significance

Precautions:
# patient may be combative if physically dependent on opioids
# should not be administered to the newborn

Question 2

Naloxone - Side Effects (5)

Answer 2

> agitation
> pupil dilation, excessive lacrimation (tearing)
> convulsions, tremor
> sweating, goose flesh
> nausea, vomiting

Question 3

Naloxone - Actions

Answer 3

An opioid antagonist that prevents and reverses the effects of opioids, used in patients with altered conscious state with respiratory depression secondary to opioid administration.

Question 4

Naloxone - Presentation

Answer 4

400mcg / 0.4mg in 1ml glass ampoule

Question 5

Naloxone - Dose

Answer 5

AD: 1.6-2mg in 4-5ml IM, repeat 0.8mg in 2ml @10/60 once only
PD: 10mcg/kg IM, repeated @10/60 once only

Question 6

Naloxone - Onset and Duration

Answer 6

IM effects:

• onset: 1-3 mins
• duration: 30-45 mins