Misoprostol

Question 1

Misoprostol
Contraindications (2)
Precautions (1)

Answer 1

Contraindications:

• allergy to prostaglandins
• exclude multiple pregnancy before administration

Precautions: 
# history of asthma

Question 2

Misoprostol - Side Effects (4)

Answer 2

• hyperpyrexia / fever >41.5 degrees
• shivering
• abdominal pain
• diarrhoea

Question 3

Misoprostol - Actions

Answer 3

A synthetic prostaglandin that enhances uterine contractions, as indicated in cases of primary postpartum haemorrhage where fundus remains not firm despite fundal massage and the suckling of the newborn.

Question 4

Misoprostol - Presentation

Answer 4

200mcg tablet

Question 5

Misoprostol - Dose

Answer 5

In PPH:

800mcg (4 tablets) orally, once only

Question 6

Misoprostol - Onset and Duration

Answer 6

Oral effects:

• onset 8-10 mins
• duration 2-3 hours