Morphine

Question 1

Morphine
Contraindications (3)
Precautions (7)

Answer 1

Contraindications:

• hypersensitivity
• late second stage labour
• renal impairment / failure

Precautions: (HACE-BMA)

# H: hypotension
# A: opioid addiction / acute alcoholism 
# C: COPD / respiratory depression
# E: elderly / frail patients

# B: burns involving the respiratory tract
# M: monoamine oxidase inhibitors (anti- depressants) 
# A: current asthma

Question 2

Morphine - Side Effects (8)

Answer 2

Central Nervous System effects:

• euphoria
• drowsiness
• addiction
• pin point pupils
• respiratory depression
• nausea / vomiting

Cardiovascular effects:

• bradycardia
• hypotension

Question 3

Morphine - Actions

Answer 3

An opioid analgesic with
Central Nervous System effects: CNS depression resulting in analgesia, respiratory depression and suppression of the cough reflex
and
Cardiovascular effects: vasodilation and decreased conduction velocity through the AV node

Question 4

Morphine - Presentation

Answer 4

10mg in 1ml ampoule

Question 5

Morphine - Onset and Duration

Answer 5

IV effects:

• onset: 2-5 mins
• peak: 10 mins
• duration: 1-2 hours

IM effects:

• onset: 10-30 mins
• peak: 30-60 mins
• duration: 1-2 hours