Mycology Flashcards

1
Q

Study of fungi

A

Mycology

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2
Q

2 Forms

A
  • Molds

* Yeasts

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3
Q

– multicellular
– filamentous (hyphae)
– live at RT- 25C

A

Molds

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4
Q

– unicellular
– nonfilamentous
– live at RT- 37C

A

Yeasts

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5
Q

Characteristics

A
  • Saprophytic
  • Dimorphic
  • Multicellular
  • Plant-like
  • Parasitic
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6
Q

Eat decomposing organic matter

A

Saprophytic

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7
Q

– Some

– Can live as a yeast in the body + molds outside

A

Dimorphic

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8
Q

Except yeats

A

Multicellular

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9
Q

CW: Chitin

A

Plant-like

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10
Q

Can cause disease

A

Parasitic

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11
Q

Morphology

A
  • Hyphae
  • Septae
  • Conidia abd Spores
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12
Q
  • Collective – mycelium

* Tubular structures – filamentous

A

Hyphae

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13
Q

– cross thin walled structures
– inside ye hyphae
– divides the hyphae

A

Septae

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14
Q

Means of asexual reproduction

A

Conidia and Spores

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15
Q

Phyla

A
  • Phylum Glomerulomycota
  • Phylum Ascomycota
  • Phyllum Basidiomycota
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16
Q

– Former: Phylum Zygomycota
– Sexual: Zygospore
– Asexual: Sporangium

A

Phylum Glomerulomycota

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17
Q

– largest Phylum
– Sexual: Ascus (sac) ascopores
– “Sac fungi”
– Asexual: Conida

A

Phylum Ascomycota

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18
Q

– “Club fungi”
– Sexual: Basidiospores
– Asexual: Spores/ Conidia

A

Phylum Basidiomycota

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19
Q

– Study of fungal diseases (mycoses) & associated tx

A

Medical Microbiology

  • Hypersensitivity
  • Mycotoxicosis
  • Mycetisma
  • Fungal Infections
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20
Q

CA: Resporatory allergen/ conida (inhaler)

A

Hypersensitivity

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21
Q

– Ingestion of pre-formed fungal toxin
– Ex: state peanuts — Aflatoxin
wheat — Ergotoxin
– large amount of Aflatoxin — hepatocellular carcinogen

A

Mycotoxicosis

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22
Q

– ingestion of a poisonous fungi

– ex: Amanita phalloides

A

Mycetisma

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23
Q

Fungal infections

A
  • Superficial Mycose
  • Cutaneous Mycoses
  • Subcutaneous Mycoses
  • Systemic Mycoses
  • Opportunistic Mycoses
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24
Q

– Epidermis
– most common fungal infection
– affects: skin, hair, nails (Keratin)
– s/sx: hypo/hyperpigmentation

A

Superficial Mycoses

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25
Q

Superficial Mycoses

A
  • Black piedra
  • White piedra
  • Pityriasis
  • Tinea nigra
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26
Q

– aka Tinea nodosa
– CA: Peidraia hortae
– CM: BLACK nodules found

A

Black piedra

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27
Q

– CA: Trichosporin beigelii

– CM: BEIGE nodules found

A

White piedra

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28
Q

– An an
– aka Tinea versicolor
– CA: Malassezia furfur
- CM: hypo/hyper pigmented irregular serpentine patches

A

Pityriasis

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29
Q

– CA: Exophiala (Hortae) Werneckii

– CM: Dark-brown balck particles on the palms and soles

A

Tinea nigra

30
Q

Cutaneous Mycoses
— Dermis
– CA: dermatophytes

A
  • Epidermophyton – skin, nails
  • Microsporum – skin, hair
  • Trichophyton – skin, nails, hair
31
Q

Cutaneous Mycoses

A
  • Tinea pedis
  • Tinea cruris
  • Tinea unguium
  • Tinea corporia
  • Tinea barbae
  • Tinea capitis
32
Q

– L: Feet
– Dermatophyte: T. Rubrum
T. Mentagrophytes
E. Floccosum

A

Tinea pedis

33
Q

– L: Groin Area (Jock itcht)

– Dermatophyte: Same

A

Tinea cruris

34
Q

– L: Hands/ nails

– Dermatophyte: same

A

Tinea unguium

35
Q

– L: Trunk
– Dermatophyte: T. Rubrum
E. Floccosum

A

Tinea corporis

36
Q

– L: Beard area

– Dermatophyte: T. Mentagrphytes

A

Tinea barbae

37
Q

– L: Scalp/ head
– Dermatophyte: T. Mentagrophytes
M. Canis

A

Tinea capitis

38
Q

– Hypodermis, muscles, tissues.

– Lesions are usually introduced through a trauma on the skin

A

Subcutaneous Mycoses

39
Q

Subcutaneous Mycoses

A
  • Chromoblastomycosis
  • Mycetoma
  • Sporotrichosis
  • Phaeohyphomycosis
40
Q

– CA: Fonsacaea pedrosoi
F. impacta
Phialaphora verrucosa (MC)
– CM: Verrucous/ Warty like lesions found along the drainings of lyphatics

A

Chromoblastomycosis

41
Q
– Madura Foot
– Commonly associated with bare foot individuals
– CM: Suppuration/ Abcess formation
           Granuloma formation
           Formation of draining
A

Mycetoma

42
Q

– Occupational disease of Gardeners
– Habitat: Soil, tree bark, rose thorns
– CM: Nodules, Ulceration along the draining lymphatics

A

Sporotrichosis

43
Q

Tx: DOC for Sporotrichosis

A

KI Solution

44
Q

– CA: Dermatiaceous molds
– CM: Solitary encapsulated cysts, rhinitis/ sinusitis
Formation of brain abcess

A

Phaeohyphomycosis

45
Q

– Blood
– Endemic Mycoses
– CA: Dimorphic fungi
– 1st site: Respirator system/ lungs

A

Systemic mycoses

46
Q

Tx to Systemic Mycoses

A
  • Mild to Moderate: Itraconazole

* Moderate - Severe: Amphotericin B

47
Q

Systemic Mycoses

A
  • Coccidioimycosis
  • Histoplasmosis
  • South American Balstomycosis
  • North American Blastomycosis
48
Q

– CA: Coccidiodies immites
podasii
– aka Valley Fever
Dessert Rheumatism

A

Coccidioimycosis

49
Q

– Histoplasma capsulatum
– aka Spelunker’s Disease
– MOT: Bat droppings
– CM: Mimics rhe s/sx of PTB

A

Histoplasmosis

50
Q

– CA:Paracoccidiodes bracillensis

– CM: Primary Lung lesions

A

South American Blastomycosis

51
Q

– CI: Blastomycoses dermatitis

– CM: Pulmonary infiltrates

A

North American Blastomycosis

52
Q
  • Immunocompromised
A

Opportunistic Mycoses

53
Q

Opportunistic Mycoses

A
  • Candidiasis
  • Cryptococcosis
  • PJP
  • Aspergillosis
  • Mucormycosis
54
Q

– most common

– CA: Candida albicans

A

Candidiasis

55
Q

CM of Candidiasis

A
  • Cutaneous/ Mucous
  • Systemic
  • Chronic Mucocutaneous
56
Q

– Intertriginous infxn
– oral thrush
– onyehomycosis
– Vulvovaginitis

A

Cutaneous/ Mucous

57
Q

Tx for Cutaneous/ Mucous

A
  • Ketoconazole

* Nystatin

58
Q

– in persons

– associated with indwelling catheters & prosthetic devices

A

Systemic

59
Q

– asscoiated with immunodeficiency + endocrinopathies

A

Chronic Mucocutaneous

60
Q

Tx for Systemic and Chronic Mucocutaneous

A
  • Amphotericin B

* Fluconazole

61
Q
– Biomarker for AIDS
– CA: Cryptococcus neoformans
– MOT: Pigeon Transmission
– ID Test: India Ink
– CM: Meningitis/ Crytococcal Meningitis
A

Crytococcosis

62
Q

Tx: DOC for Crytococcosis

A

Fluconazole

63
Q

Tx: Systemic for Crytococcosis

A

Amphotericin B

64
Q

Standard tx for Crytococcosis

A

Anphotericin + Flucytosine

65
Q

– Former: Protozoan

– Former: P. carini

A

PJP

66
Q

Tx: DOC for PJP

A

Co-trimoxazole

67
Q
– CA: Aspergillus fumigatus
          A. flavus
– CM: Pulmonary aspergilloma
           Invasive Aspergillosis
           Allergic bronchopulmonary aspergillosis
A

Aspergillosis

68
Q

Tx: DOC for Aspergillosis

A

Vononazole

69
Q

– CM: Rhinocerebullar infxn

– CA: Zygomucor

A

Mucomycosis

70
Q

Tx: DOC for Mucomycosis

A

Posaconazole