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Mcrbly nd Pblc Hlth > Immunology > Flashcards

Immunology Flashcards

1
Q

Study of how the body recognizes itself from nonself – antigen

A

Immunology

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2
Q

2 Types of Immune Sytem

A
  • Nonspecific Immunity

* Specific Immunity

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3
Q 
– Antigen independent
– ✖️antigen recognition
– Immediate response
– ✖️antibody production
– ✖️memory
A

Innate Immunity

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4
Q 
– Antigen dependent 
– Antigen recognition
– Lag time for response 
– Results to immunologic memory
– Antibody production
A

Specific Immunity

— Acquired

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5
Q

B cells

A

Humoral Immunity

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6
Q

T cells

A

Cellular- Mediated immunity

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7
Q

Cells Involved

A
  • Granulocytes

* Agranulocytes

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8
Q
  • Basophils
  • Eosinophils
  • Netrophils
A

Granulocytes

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9
Q

Bone marrow, T cels

A

Granulocytes

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10
Q

Histamine release

A

Basophils

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11
Q

– Responsible for Type I HS/ Allergy

– ⬆️ during HELMINTHIC infestations

A

Eosinophils

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12
Q

– Most abundant/ abundant
– first to respond (inflammation) acute
– ⬆️ during BACTERIAL infection

A

Neutrophils

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13
Q

Agranulocytes

A
  • Macrophages

* Lymphocytes

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14
Q

– Monocytes - young macrophages

– 1’ phagocytosis

A

Macrophages

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15
Q

Lymphocytes

A
  • B Lymphocytes

* T Lymphocytes

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16
Q

– B cells
– Mature in bone marrow
– 1’ antigen presentation

A

B Lymphocytes

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17
Q

Mature B cells

A
  • Plasma cells

* Memory cells

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18
Q

Antibody/ Ig production

A

Plasma Cells

19
Q

Immunologic cells

A

Memory cells

20
Q

T Lymphocytes
– T cells
– Soldier

A
  • Helper T cells

* Cytotoxic T cells

21
Q

– CD4 cells

– inactivate B cells & cytotoxic T cells

A

Helper T cells

22
Q

– attaches to the membrane of the pathogen & initiates an attack
– CD8 cells
– counteracts neoplastic cells

A

Cytotoxic T cells

23
Q

Nonspecific Immunity

A
  • Inflammation
  • Phagocytosis
  • Complement System
24
Q

Inflammation

A
  • Rubor — redness
  • Dolor — pain
  • Calor — heat
  • Function Leasa — loss of function
  • Tumor
25
Q
  • Acute I - Neutrophil

* Chronic I - Macrophage

A

Phagocytosis

26
Q

Three Types of Complement System

A
  • Classical Pathway
  • Alternative
  • Mannose-Binding Lecithin
27
Q

1’ Goal of Compelent System

A

To produce the membrane attack complex (MAC))

28
Q

Specific Immunity / Adaptive Immunity

A
  • Humoral Immunity

* Cell-mediated Immunity

29
Q

Mediated by B cells (plasma cells)

A

Humoral Immunity

30
Q

Mediated by T cells

A

Cell-mediated immunity

31
Q

Types of immunoglobulins

A
  • IgA
  • IgE
  • IgG
  • IgM
  • IgD
32
Q

– secretory Ig

– found in body secretions

A

IgA

33
Q

– degranulation of mast cells

– responsible for Type I HS rxn

A

IgE

34
Q

– ✔️ BBB

– Most dominant

A

IgG

35
Q

– aka macroglobulin
– largest Ig
– First Ig to respond; acute infection

A

IgM

36
Q

– no known function

– dound in B cell receptors

A

IgD

37
Q

Types of HS reaction

A
  • Antibody-mediated HS reaction

* Cell-mediated HS reaction

38
Q

Antibody-mediated HS rxn

A
  • Type 1 HS rxn
  • Type 2 HS rxn
  • Type 3 HS rxn
39
Q

– immediate HS rxn
– mediated by IgE
– Allergic rxn, anaphylactic rxn

A

Type 1 HS rxn

40
Q

– mediated by IgE (more), IgM
– Ab binds to the surface of the pathogen
– blood transfusion incompatibility
– Grave’s disease

A

Type 2 HS rxn

41
Q

– mediated by IgG
– antigen-antibody complex formation
– Rheumatic Heart disease
– Acute glomerular nephritis

A

Type 3 HS rxn

42
Q

Cell-mediated HS rxn

A

Type 4 HS rxn

43
Q 
– delayed HS rxn
– ✖️ Ab involved
– mediated by helper T cells
– attopic dermatitis
– tuberculin skin rxn — PPD test
A

Type 4 HS rxn

Mcrbly nd Pblc Hlth (10 decks)

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