mycobacteria Flashcards

1
Q

Pott’s disease

a. mycobacterium tuberculosis
b. mycobacterium leprae
c. mycobacterium ulcerans
d. mycobacterium africanum

A

M. tuberculosis
- pott’s disease

M. leprae

  • Hansen bacillus
  • leprosy

M. ulcerans

  • inert bacillus
  • buruli ulcer

M. africanum
- pulmonary disease

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2
Q

which of the following skin tests is for M. tuberculosis

a. purified protein derivative
b. fernandez skin test
c. mitsuda skin test

A

M. tuberculosis
- skin test : PPD (PURIFIED PROTEIN DERIVATIVE)
aka MANTOUX / VON PIRQUET TEST
VOLMER TEST - obsolete

skin test for M. leprae

  1. Fernandez / early reaction
    2. Mitsuda / late reaction
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3
Q

inert bacillus

a. mycobacterium tuberculosis
b. mycobacterium leprae
c. mycobacterium ulcerans
d. mycobacterium africanum

A

M. tuberculosis
- pott’s disease

M. leprae

  • Hansen bacillus
  • leprosy

M. ulcerans

  • inert bacillus
  • buruli ulcer

M. africanum
- pulmonary disease

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4
Q

tuberculosis in animals / cattles

a. mycobacterium tuberculosis
b. mycobacterium leprae
c. mycobacterium ulcerans
d. mycobacterium bovis

A

M. tuberculosis
- pott’s disease

M. leprae

  • Hansen bacillus
  • leprosy

M. ulcerans

  • inert bacillus
  • buruli ulcer

M. bovis
- cause tb in animals / cattles

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5
Q

agent of hansen’s disease

a. mycobacterium tuberculosis
b. mycobacterium leprae
c. mycobacterium ulcerans
d. mycobacterium bovis

A

M. tuberculosis
- pott’s disease

M. leprae

  • Hansen bacillus
  • leprosy

M. ulcerans

  • inert bacillus
  • buruli ulcer

M. bovis
- cause tb in animals / cattles

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6
Q

what are the lepra cells

a. monocyte
b. neutrophil
c. macrophage
d. leukcytes

A

lepra cells

: MACROPHAGE WITH INGESTED AFB

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7
Q

which of the two types of leprosy has a thickening of skin

a. tuberculoid/ paucibacillary disease
b. multibacillary/ lepromatous disease

A

tuberculoid / paucibacillary disease

  • few hypopigmentation
  • red skin lesion

multibacillary / lepromatous disease

  • widespread skin involvement
  • nodules
  • thickening of the skin
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8
Q

which of the following skin tests is for M.leprae

a. purified protein derivative
b. fernandez skin test
c. mitsuda skin test

A

M. tuberculosis
- skin test : PPD (PURIFIED PROTEIN DERIVATIVE)
aka MANTOUX / VON PIRQUET TEST
VOLMER TEST - obsolete

skin test for M. leprae

  1. Fernandez / early reaction
    2. Mitsuda / late reaction
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9
Q

tap water bacillus

a. m. tb
b. m. ulcerans
c. m. gordonae
d. m, marinum

A

M. tuberculosis
- pott’s bacillus

M. ulcerans

  • inert bacillus
  • buruli ulcer

M. gordonae
- tap water bacillus

M. marinum

  • of the sea
  • swimming pool granuloma
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10
Q

battey bacillus

a. M. marinum
b. M. gordonae
c. M. avium
d. M. gastri

A

M. gordonae
- tap water bacillus

M. marinum

  • of the sea
  • swimming pool granuloma

M. avium - itracellulare complex
- battery bacillus

M. gastri
- J bacillus

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11
Q

yellow bacillus

a. M. terrae
b. M. gordonae
c. M. avium
d. M. kansaii

A

M. terrae
- roddish bacillus

M. marinum

  • of the sea
  • swimming pool granuloma

M. avium - itracellulare complex
- battery bacillus

M. kansaii
- yellow bacillus , due to beta carotene

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12
Q

measures the component of the cell mediated immune response to mycobacteria tuberculosis to diagnose latent tb infection and tb disease

a. ethanol heat shock spore test
b. stromy clot test
c. interferron gamma release assay
d. quantiferon gold assay

A

EHSST
-differentiate Clostridium form Acteroides

Stormy clot test
- Clostridium perfringes

QUANTIFERRON TUBERCULOSIS GOLD ASSAY / IGRA
- to diagnose laten tb infection and tb disease

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13
Q

what is the specimen to use in IGRA

a. edta tube
b. sps
c. heparinized blood
d. whole blood

A

heparinized blood

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14
Q

based on DOH how many sputum to pass in laboratory for testing for tb

a. 2 sputum
b. 4 sputum
c. 1 sputum
d. aota

A

2 sputum for AFB AND DSSM

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15
Q

IN RONYOUN GROUP WHAT GROUP IS MYCOBACTERIUM KANSASII

A. photochromogens

b. scotochromogen
c. non photochromogen
d. rapid growers

A

group 1: photochromogens

  • M. marinum
  • M. asiaticum
  • M. simiae
  • M. kansasii

(mask)

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16
Q

IN RONYOUN GROUP WHAT GROUP IS MYCOBACTERIUM GORDONAE

A. photochromogens

b. scotochromogen
c. non photochromogen
d. rapid growers

A

GROUP II - SCOTOCHROMOGENS

  • M. scrofulaceum
  • M. szulgai
  • M. xenopi
  • M. gordonae
  • M. flavescens
  • M. thermosistible
17
Q

IN RONYOUN GROUP WHAT GROUP IS MYCOBACTERIUM malmoense

A. photochromogens

b. scotochromogen
c. non photochromogen
d. rapid growers

A

GROUP III - NONPHOTOCHROGENS

  • M. malmoense
  • M. avium
  • M. ulcerans
    - M. gastri
    - M. haemophilum
    - M. terrae- triviela

(MAUGHT)

18
Q

IN RONYOUN GROUP WHAT GROUP IS MYCOBACTERIUM FORTUITUM

A. photochromogens

b. scotochromogen
c. non photochromogen
d. rapid growers

A

GROUP IV - RAPID GROWERS

  • M. SMEGMATIS
  • M. PHLEI
  • M. FORTUITUM - CHELONAE
19
Q

which of the following agar is non selective agar based

a. lowenstein jensen
b. petraganni
c. american thoracic society
d. middlebrook 7H10

A

NON SELECTIVE : EGG BASED

  1. LJ
  2. PETRAGANNI
  3. AMERICAN THORACIC SOCIETY

NON SELECTOVE : AGAR BASED

  1. MIDDLEBROOK 7H10
  2. MIDDLEBROOK 7H11
20
Q

which of these stain is color blind

a. auramine rhodamine
b. spenger
c. acid fast staim
d. file franco

A

spenger stain

  • color blind stain
  • organisms are stained black
21
Q

tests to differentiate MTB FROM M. bovis

a. colonial morphology
b. growth temperature
c niacin accumulation
d. nitrate reduction

A

NIACIN REDUCTION
- reagent: CYANOGENBROMIDE
- (+) yellow
!!!!! all mycobacteria produces niacin . most of themwith enzymes will convert niacin to niacin ribonucleotide
!!!! MTB LACKS THIS ENZYME. THEREFOR MTB IS NIACIN (+)

DIFFERENTIATE MTB FROM M. BOVIS

22
Q

what mycobacteria can grow on 5% NaCl

a. m. marinum
b. m. leprae
c. m. terrae
d. mtb

A

5% nacl grwoth - M. terrae- triviale