myasthenia graves and LES Flashcards
1
Q
MG - autoantibodies to ?
A
post synaptic Ach receptors
2
Q
features of MG?
A
muscles become progressively weaker after periods of activity and slowly improve after rest
3
Q
what conditions is MG associated with?
A
autoimmune conditions such as SLE
4
Q
Where on the body does MG affect?
A
face, neck, limb girdles, eyes, dysphagia and diplopia
5
Q
why do you get diplopia?
A
extra ocular muscle weakness
6
Q
Investigations MG?
A
single fibre electromyography
CT to exclude thyoma
7
Q
CK levels in MG?
A
normal
8
Q
treatment of MG?
A
long acting acetylcholine esterase
pyridostigmine MGP
9
Q
what do you get antibodies against in Lambert Eaton Syndrome?
A
pre synaptic voltage gated calcium channels
10
Q
what is lambert eaton syndrome associated with/
A
small cell lung cancer
