Mutations and Gene Editing Flashcards
Gene Mutation
A change in sequence of bases of a particular gene
Substitution
One nucleotide is swapped for another
Insertion
The addition of one or more nucleotides into a segment of DNA
Deletion
The loss of one or more nucleotides from a segment of DNA
Frameshift
A mutation that messes up the three base pair codons
either insertion or deletion
Mutagen
An agent that causes genetic mutations
Germ Cell
A cell that develops into a reproductive cell
Gene Knockout
Genetically modified organisms that lack a functional copy of a gene
Mutant
An organism arising from an instance of mutation
CRISPR Sequences
Clustered Regularly Interspaced Short Palindromic Repeats
Cas9 Enzyme
A programmable enzyme that allows targeted split of DNA in virtually any organism
Genome Editing
A method used for making specific changes to the DNA of a cell or organism
Conserved Sequences
Identical or similar sequences in nucleic acids (DNA and RNA) or proteins across species