musculoskeletal diseases Flashcards

1
Q

achondroplasia

A

This chondrodystrophy, characterized by an abnormality in conversion of cartilage to bone, is the most common form of short-limb dwarfism; characterized by short stature with rhizomelic shortening of the limbs, large head with frontal bossing and midface hypoplasia, exaggerated lumbar lordosis,

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2
Q

ankylosing spondylitis

A

rthritis of the spine, resembling rheumatoid arthritis, which may progress to bony ankylosis with ossification of the anterior and posterior longitudinal ligaments; the disease is more common in males

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3
Q

arthritis

A

joint inflammation

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4
Q

inflammation

A

a protective tissue response to injury or destruction of tissues

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5
Q

rheumatoid

A

arthritis characterized by inflammatory changes in body’s connective tissues

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6
Q

chondrosarcoma

A

malignant tumor of cartilage

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7
Q

degenerative joint disease

A

joint disease characterized by degeneration of the articular cartilage

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8
Q

Ewing tumor

A

cancerous tumor that invades the entire shaft of bone

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9
Q

sarcoma

A

connective tissue tumor

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10
Q

gout

A

systemic disease due to deposition of urate crystals

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11
Q

Hurler syndrome

A

caused by irregular ossification and is due to an overproduction of mucopolysaccharides. symptoms: short stature, skeletal deformities, enlarged organs

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12
Q

mucopolysaccharides

A

an antiarthritic compound that increases the viscosity (stickiness) of synovial fluid

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13
Q

hypophosphatasia

A

deficiency in alkaline phosphatase

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14
Q

alkaline phosphatase

A

enzyme produced in the bone and liver

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15
Q

Legg-Calve-Perthes disease

A

disease of hip joint that results in a loss of bone mass due to inadequate blood flow to the joint

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16
Q

Marfan syndrome

A

abnormal formation of connective tissue. symptoms: long, slender habitus, skeletal malformation

17
Q

multiple myeloma

A

tumor derived from blood cells

18
Q

Osgood-Schlatter disease

A

disease that affects the tibial tubercle, where the patella inserts onto the tibia. manifests when growth centers become stressed (usually due to athletic activity

19
Q

osteochondritis dissecans

A

osteochondrosis involving the joints, particularly the shoulder and knee

20
Q

osteochondrosis

A

group of developmental disorders that affect ossification centers and usually occur in adolescence

21
Q

osteogenesis imperfecta

A

abnormal formation of connective tissue

22
Q

osteoid osteoma

A

benign lesion that can occur in any bone, but most common in the long bones.

23
Q

osteomyelitis

A

bacterial infection of bone, can be fungal too. most common pathogen is staphylococcus aureus.

24
Q

staphylococcus aureus

A

staph bacteria found in nasal membranes, skin, hair follicles and perineum.

25
Q

osteoporosis

A

low bone density to allow for proper support

26
Q

kyphosis

A

forward hunching of spine

27
Q

Paget disease

A

degenerative disorder of bone resulting in softening and swelling of bone.

28
Q

psoriatic arthritis

A

psoriasis is a chronic skin disease which can cause scaling, dryness, pustules and abscesses to appear on nails, scalp, spine and genitalia. when joints are involved its called psoriatic arthritis.

29
Q

Reiter syndrome

A

arthritis associated with nonbacterial urethritis, conjunctivitis, cervicitis and mucocutaneous lesions.

30
Q

rickets

A

occurs in infants as a result of overgrowth of poorly mineralized bone and enlarged marrow cavities.

31
Q

Scheuermann disease

A

affects the ossification centers of the vertebrae

32
Q

scoliosis

A

lateral curvature of the spine in the erect position. caused by malalignment of the vertebrae.