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Drugs > Musculoskeletal > Flashcards

Musculoskeletal Flashcards

1
Q

Zanaflex

tizanidine (PO)

A

Pharmacologic category: alpha2 agonist
Common indication: spasticity
Key side effects: drowsiness, hypotension, dizziness, xerostomia, weakness

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2
Q

Plaquenil

hydroxychloroquine (PO)

A

Pharmacologic category: aminoquinolone
Common indication: RA, SLE, malaria
Key side effects: retinal toxicity, rash, diarrhea
Other Notes: use has been associated with cardiomyopathy, bone marrow suppression, and neuromuscular effects (i.e., myopathy, palsies, and progressive weakness)

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3
Q

Colcrys

colchicine (PO)

A

Pharmacologic category: antigout agent
Common indication: gout
Key side effects: diarrhea, nausea, vomiting, bone marrow suppression, myotoxicity (including rhabdomyolysis)

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4
Q

Voltaren

diclofenac (PO)

A

Pharmacologic category: NSAID
Common indication: OA, RA, acute pain
Key side effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea
US Boxed Warnings; may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation
Other Notes: may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)

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5
Q

Motrin, Advil

ibuprofen (PO)

A

Pharmacologic category: NSAID
Common indication: OA, RA, acute pain
Key side effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea
US Boxed Warnings: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation
Other Notes: may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)

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6
Q

Mobic

meloxicam (PO)

A

Pharmacologic category: NSAID
Common indication: OA, RA, acute pain
Key side effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea
US Boxed Warnings: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation
Other Notes: may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)

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7
Q

Relafen

nabumetone (PO)

A

Pharmacologic category: NSAID
Common indication: OA, RA, acute pain
Key side effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea
US Boxed Warnings: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation
Other Notes: may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)

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8
Q

Feldene

piroxicam (PO)

A

Pharmacologic category: NSAID
Common indication: OA, RA, acute pain
Key side effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea
US Boxed Warnings: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation
Other Notes: may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)

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9
Q

Indocin

indomethacin (PO)

A

Pharmacologic category: NSAID
Common indication: OA, RA, acute pain, gout
Key side effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea
US Boxed Warnings: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation
Other Notes: may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)

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10
Q

Toradol

ketorolac (PO, IV)

A

Pharmacologic category: NSAID
Common indication: Pain
Key side effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea
US Boxed Warnings: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation; indicated for short term use (<= 5 days)
Other Notes: may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)

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11
Q

Celebrex

celecoxib (PO)

A

Pharmacologic category: NSAID, COX-2 selective
Common indication: OA, RA, acute pain
Key side effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea
US Boxed Warnings: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events; may increase the risk for serious (and potentially fatal) gastrointestinal adverse events including ulceration, bleeding, and perforation
Other Notes: may reduce renal blood flow and compromise existing renal function (avoid in patients with renal disease, heart failure, and cirrhosis)

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12
Q

Voltaren Gel, Solareze

diclofenac (topical)

A

Pharmacologic category: NSAID
Common indication: OA
Key side effects: pruritis, rash

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13
Q

Flexeril

cyclobenzaprine (PO)

A

Pharmacologic category: skeletal muscle relaxant
Common indication: muscle spasm
Key side effects: drowsiness, dizziness, xerostomia, fatigue
Other Notes: use may cause prolonged cardiac arrhythmias, and tachycardia; CI within 14 days of MAOI inhibitor therapy

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14
Q

Lioresal

baclofen (PO)

A

Pharmacologic category: skeletal muscle relaxant
Common indication: spasticity
Key side effects: drowsiness

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15
Q

Soma

carisoprodol (PO)

A

Pharmacologic category: skeletal muscle relaxant
Common indication: muscle spasm
Key side effects: drowsiness
Other Notes: drug abuse potential

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16
Q

Robaxin

methocarbamol (PO)

A

Pharmacologic category: skeletal muscle relaxant
Common indication: muscle spasm
Key side effects: drowsiness

17
Q

Skelaxin, Metaxall

metaxalone (PO)

A

Pharmacologic category: skeletal muscle relaxant
Common indication: muscle spasm
Key side effects: drowsiness

18
Q

Norflex

orphenadrine (PO)

A

Pharmacologic category: skeletal muscle relaxant
Common indication: muscle spasm
Key side effects: drowsiness, dizziness, xerostomia, fatigue
Other Notes: use caution in patients with cardiac disease

19
Q

Marcaine, Sensorcaine

bupivacaine (IV)

A

Pharmacologic category: local anesthetic
Common indication: epidural anesthesia
Key side effects: hypotension
US Boxed Warning: bupivavcaine 0.75% should not be used for obstetrical anesthesia due to reports of cardiac arrest and death
Other Notes: ISMP-high alert medication

20
Q

Transdermal: Lidoderm; IV: Xylocaine

lidocaine (transdermal, IV)

A

Pharmacologic category: transdermal: topical analgesic; IV: antiarrhythmic
Common indication: transdermal: pain; IV: ventricular arrhythmias
Key side effects (transdermal): dermatitis, erythema, urticaria, skin depigmentation, skin edema
Key side effects (IV): bradycardia
Other Notes: ISMP-high alert medication (IV), patch may remain in place for up to 12 hours in any 24 hour period, patch may be cut

21
Q

Zyloprim

allopurinol (PO)

A

Pharmacologic category: xanthine oxidase inhibitor
Common indication: gout
Key side effects: diarrhea, nausea, rash, leukopenia, thrombocytopenia
Other Notes: rare association with severe (and potentially fatal) allopurinol hypersensitivity syndrome (risk highest in certain Asian populations)

Drugs (11 decks)

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