muscular system Flashcards
myofibrils
contain microfilaments divided into sarcomeres
sarcomeres
individual contractile units separated by a border (Z-line)
sarcoplasmic reticulum
stores calcium and surrounds myofibrils
sarcoplasm
same thing as cytoplasm
sarcolemma
plasma membrane of muscle cells that can propogate action potentials that are invaginated by T-tubules (channels for ion flow)
mitochondria
present in large amounts in myofibrils
as submaximal stimulus increases
motor unit recruitment increases
when a maximum stimulus is reached
all motor units are recruited
cardiac muscle
- striated muscle
- one or two central nuclei
- cells separated by intercalated discs that have gap junctions
- lots of mitochondria
smooth muscle
- lacks striation
- one central nucleus
- stimulated by autonomic nervous system
- does not utilize sarcomeres
skeletal muscle
- striated
- multiple nuclei
neuromuscular pathway
- action potential of a neuron releases ACh at a neuromuscular junction
- an action potential is generated on the sarcolemma and throughout T-tubules
- sarcoplasmic reticulum releases calcium
- calcium binds to troponin on the actin helix, allowing myosin to bind
- myosin cross-bridges form and contraction occurs
sliding filament model (contraction)
- calcium exposes binding sites on actin
- myosin head attached to actin filament cross-bridge
- inorganic phosphate is released from the myosin head initiates power stroke
- new ATP attaches to myosin head –> cross bridges unbind myosin and actin unbind
- when ATP is converted to ADP+Pi, the myosin head is cocked back
what happens if no ATP is available
the muscle is stuck in contraction (rigor mortis)
think filaments
actin