Muscle Structure and Function Flashcards

1
Q

How much skeletal muscle is present in normal young people?

A
  • About 40% male bodyweight

- About 30% female bodyweight

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2
Q

What is the principle function of skeletal muscle and how does it do this?

A
  • Principle function is contraction/ shortening distance between bones.
  • Skeletal muscle moves bones attached to it by tendons.
  • Muscle groups work together
  • When a muscle contracts, its insertion is pulled towards its origin.
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3
Q

Where does more force come from in skeletal movement?

A
  • More complete activation of one muscle
  • More activation of agonist muscle
  • More inactivation of antagonist muscles.
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4
Q

What are the levels of skeletal muscle structure from most superficial to deep?

A
  • Whole muscle
  • Fasicles
  • Muscle fibre (cell)
  • Myofibrils
  • Sarcomeres
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5
Q

What are fasicles?

A

-Bundles of cells surrounded by connective tissue

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6
Q

What provides strength of muscle fibres?

A

-Strength of muscle fibres comes from bundling.

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7
Q

What are the histological layers of skeletal muscle?

A
  • Thick epimyseium
  • Perimyseium
  • Endomyseium
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8
Q

What is a motor unit?

A
  • A single motor neurone and all the muscle fibres it innervates.
  • The functional units of motor control
  • Final common pathway for info leaving the CNS.
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9
Q

How many motor units does a muscle contain and how many muscle fibres would a motor unit contain?

A
  • A muscle may contain 100’s of motor units and each motor unit may contain 100’s of muscle fibres.
  • These ammounts will relate to the function of the muscle in question and the size of the muscle.
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10
Q

What factors would impact no. of fibres, motor units and muscle fibres in a motor unit?

A
  • No. of fibres = size of muscle
  • No. of motor units = size and funtion
  • No. of muscle fibres in a motor unit = function
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11
Q

What are some things to be careful about when talking about motor units?

A
  • Muscle characteristics are different species by species.
  • In any one species, different muscles have different properties.
  • In any one muscle in any one species, the motor units have very different properties.
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12
Q

What are some classification properties of motor units?

A

-Mechanical: twitch responses; speed, force, rate of fatigue.
-Histological: metabolic profile; oxidative, glycolytic; aerobic or anaerobic, myosin ATPase activity
-Motor neurone properties: cell body size, axon diameter, synaptic inputs, axon branching
-Other: Colour; red/white
Use; phasic (tends to be pale, more glycolytic, faster contracting and fatiguing)/tonic (tends to be red, oxidative, slow contracting.

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13
Q

What is the most simple and common motor unit classification?

A

-By speed of contraction and fatigue rate

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14
Q

What are the 3 main types of motor units?

A
  • Slow (S or type 1) (smaller twitch, slower fatigue)
  • Fast fatigue resistant (FFR, 2a)
  • Fast fatiguing (FF, 2b, 2x etc.) (larger twitch, faster fatigue)
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15
Q

What determines the properties of motor units?

A
  • Genetics
  • Probably pattern of use
  • Probably not training
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16
Q

What is the training response in humans?

A
  • Changes muscle size
  • Changes properties like strength and endurance
  • In humans evidence for changes in fibre type is poor.
  • Thus it can be deduced that training in humans causes selective hypertrophy rather than type conversion.
17
Q

What is the muscles response to strength training?

A
  • Early changes: better motor unit activation, less antagonist activation, improved glycolytic metabolism
  • After 6 weeks: FF fibre hypertrophy
18
Q

What is the muscles response to endurance training?

A
  • Enhanced oxidative metabolic profile
  • More mitochondria
  • Improved O2 supply
  • More myoglobin
  • Slow and FFR fibre hypertrophy
19
Q

What types of fibres are associated with high force output?

A

-Associated with more type II fibres

20
Q

What types of fibres are associated with endurance output?

A

-More type 1 fibres

21
Q

What is fatigue?

A

-Is a failure to produce the desired/expected force in the short/long term

22
Q

What stages of skeletal muscle activation are mostly affected by fatigue?

A

-In summary, mainly affects: failure of t-tubule system and less effective Ca+ release and uptake.