Muscle - BSC Flashcards
anesthesia
?
cryesthesia
?
kinesthesia
detection of bodily position, weight, or movement of muscles, tendons, or joints
paresthesia
skin sensation with no apparent cause
synesthesia
?
paralysis
loss of motor function
result of an interruption of one or more motor pathways can occur at any point between cerebrum and muscle fiber
anesthesia
total or partial loss of sensation, especially tactile sensibility, can be induced by disease, injury, or anesthetic drugs
loss of nerve causes?
atrophy
apoptosis
programmed cell death
atrophy
?
dystrophy
form artophy specifically result of disease
necrosis
cell death (from external cause)
myopathy
muscle disease affecting muscle cell causing it to function improperly
denervation?
no necrosis of muscle cell (myonecrosis)
loss and disarray of myofilaments
don’t see rabdomyelosis***
sarcomere
Z line to Z line
skeletal muscle
voluntary contraction
peripheral contraction
primary cause of myofilament degradation in denervation atrophy?
increased proteosome activity
muscle cells tries to save energy and material so it ubiquinates
what products do lysosomes degrade
?
metalloproteinase?
extraacellular matrix activity
caspase?
play role in apoptosis and necrosis
proteosome
degrade proteins from cytoplasm
ubiquitin proteosome system
two successive steps
- target protein ubiquilated (need 4)***
- 26S proteosome recognizes ubiquitin and degrades substrate