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Top 200 > Muscarinic receptor agonist or antagonist > Flashcards

Muscarinic receptor agonist or antagonist Flashcards

1
Q

Carbachol

A

Muscarinic receptor agonist

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2
Q

Bethanechol

A

muscarinic receptor agonist

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3
Q

Pilocarpine

A

Vuity - muscarinic receptor agonist

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4
Q

Cevimeline

A

Evoxac - muscarinic receptor agonist

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5
Q

Botox

A

Botulinum toxin -indirect acting parasympatholytics

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6
Q

Daxxify

A

Botulinum toxin -indirect acting parasympatholytics

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7
Q

Atropine

A

Muscarinic receptor antagonist

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8
Q

Glycopyrrolate

A

Muscarinic receptor antagonist

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9
Q

Dicyclomine

A

Muscarinic receptor antagonist

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10
Q

Hyoscyamine

A

Muscarinic receptor antagonist

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11
Q

Scopolamine

A

Muscarinic receptor antagonist

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12
Q

Belladonna

A

Muscarinic receptor antagonist

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13
Q

Ipratropium

A

Atrovent Muscarinic receptor antagonist

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14
Q

Tiotropium

A

Spiriva Muscarinic receptor antagonist

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15
Q

Tolterodine

A

Detrol Muscarinic receptor antagonist

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16
Q

Fesoterodine

A

Toviaz Muscarinic receptor antagonist

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17
Q

Oxybutynin

A

Ditropan Muscarinic receptor antagonist

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18
Q

Darifenacin

A

Enablex Muscarinic receptor antagonist

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19
Q

Solifenacin

A

Vesicare Muscarinic receptor antagonist

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20
Q

Trospium

A

Sanctura Muscarinic receptor antagonist

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21
Q

Revefenacin

A

Yupelri Muscarinic receptor antagonist

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22
Q

Neostigme

A

Reversible cholinesterase inhibitor

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23
Q

Physostigmine

A

reversible cholinesterase inhibitor

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24
Q

Pyridostigmine

A

reversible cholinesterase inhibitor

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25
Q

Ambenonium

A

reversible cholinesterase inhibitor

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26
Q

edrophonium

A

reversible cholinesterase inhibitor

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27
Q

Malathione

ovide

A

irreversible cholinesterase inhibitor

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28
Q

Parathion

A

Is a insecticide is a irreversible cholinesterase inhibitor
When the pt inhales it is going to go in cholinergic crisis state

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29
Q

Sarin

A

Is a nerve gas that is irreversible cholinesterase inhibitor and when the pt inhales it the pt will go into cholinergic crisis and cause bronchioconstriction and dies

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30
Q

Pralidoxime

2-Pam

A

is a antidote of intoxication of irreversable cholinesterase inhibitors
If is administer before the complex between the irriversible cholinesterase inhibitor and the enzyme cholinesterase form Pralodixime will reactivate the acetyl cholinesterase

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31
Q

Nicotine

Explain the physical dependence

A
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32
Q

Varenicline

Chantix

A

Central nicotinic partial agonist

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33
Q

Vecuronium

A

Muscle nicotinic receptor antagonist

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34
Q

Atracurium

A

Muscle nicotinic receptor antagonist

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35
Q

Doxacurium

A

Muscle nictonic receptor antagonist

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36
Q

Cisatracurium

A

Muscle nicotinic receptor antagonist

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37
Q

Rocuronium

A

Muscle nicotinic receptor antagonist

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38
Q

Pipecuronium

A

Muscle nictonic receptor antagonis

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39
Q

Pancuronium

A

Muscle nicotinic receptor antagonist

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40
Q

Succinylcholine

A

Muscle nicotinic receptor agonist

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41
Q

Sugammadex

A

Reverse the effects of vecuronium and rocuronium

42
Q

Rivastigmine

A

Reversible cholinesterase inhibitor

43
Q

Donezepil

A

Reversible cholinesterase inhibitor

44
Q

DFP

Diisopropyl flurophosphate

A

Irreversible cholinesterase inhibitor use as eye drops

45
Q

Echothiophate

A

Irreversible cholinesterase inhibitor

46
Q

Dobutamine

A

B1 Selective Receptor Agonist

47
Q

Atenolol

A

B1 antagonist

48
Q

Acebutolol

A

B1 antagonist

49
Q

Betaxolol

A

b 1 receptor antagonist

50
Q

Bisoprolol

A

B1 Antagonist

51
Q

Metoprolol

Tropol XR

A

B1 receptor antagonist

52
Q

nebivolol

A

B1 receptor antagonist

53
Q

Esmolol

brevibloc

A

B1 receptor antagonist

54
Q

Ivabradine

Corlanor

A

affects the cardiac currents

55
Q

Albuterol

A

B2 agonist

56
Q

Levalbuterol

xopenex

A

Xopenex
B2 agonist

57
Q

Salmeterol

A

B2 agonist

58
Q

Formoterol

A

B2 agonist

59
Q

Alformoterol

A

b2 agonist

60
Q

Indacaterol

A

B2 receptor agonist

61
Q

Olodaterol

A

B2 agonist

62
Q

Pirbuterol

A

B2 agonist

63
Q

Vilanterol

A

B2 agonist

64
Q

Terbutaline

A

B2 agonist

65
Q

Roflumilast

Daliresp

A

PDE4 inhibitor

66
Q

Theophylline

A

Non selective Phosphodiesterase inhibitor

67
Q

Aminophylline

A

Non Selective Phosphodiesterase inhibitor

68
Q

Norepinephrine

A

Has more affinity to the Alpha subtypes
Can be metabolize by MOA and COMT

69
Q

Epinephrine

A

Has better affinity to beta receptors
Metabolize by N-demethylation or COMT

70
Q

Isoproterenol

A

Non selective Beta-adrenergic agonist

71
Q

Propranolol

Inderal

A

Non Selective B-adrenergic Antagonist

72
Q

Nadolol

A

Non selective Beta-adrenergic antagonist

73
Q

Pindolol

A

Non Selective beta-adrenergic antagonist

74
Q

Sotalol

A

Non selective Beta-adrenergic antagonist

75
Q

Timolol

A

Non selective Beta-adrenergic antagonist

76
Q

Levobunalol

A

Non selective Beta adrenergic antagonist

77
Q

Mirabegron

Myrbetriq

A

B3 Receptor Agonist

78
Q

Vibegron

Gemtesa

A

B3 Selective agonist

79
Q

Midodrine

A

Alpha 1 selective receptor agonist

80
Q

Phenylephrine

A

Alpha 1 selective agonist

Neo-Synephrine

81
Q

Pseudoephrine

A

Alpha 1 selective agonist

Sudafed

82
Q

Oxymetazoline

A

Alpha 1 selective agonist

Afrin

83
Q

Northera

A

Inderect sympathomimetic

Droxidopa

84
Q

Prazosin

Phenylethylamine back bone has quinazoline nucleus metabolize by the liver
A

Non Selective Alpha 1 antagonist
Block A1B- Blood vessels
Block A1A- Prostate and bladder

85
Q

Terazosin

Phenylethyl amine backbone Quinazoline nucleus metabolize by the liver
A

Non selective Alpha 1 antagonist
Block A1B-blood vessel
Block A1A- Prostate and bladder

86
Q

Doxazosin

6,7-methoxy phenylehtylamine back bone 2-piperazine Quinazoline nucleus metabolize by CYP in the liver
A

Non selective Alpha 1 antagonist
Blocks A1A- prostate and bladder
Blocks A1B- Blood vessels

87
Q

Alfuzosin

Does not have piperazine ring so less affinity to circulation
A

Selective Alpha a1a antagonist

88
Q

Tamsulosin

The liver hates the sulfonamide group so the drug goes directly to the kidneys Has phenylethylamine group
A

Selective Alpha 1 antagonist
A1A antagonist

89
Q

Labetalol

A

Non selective Alpha 1, Beta 1 and Beta 2 antagonist

90
Q

Carvedilol

A

Non selective alpha 1, Beta 1, Beta 2 antagonist

91
Q

Clonidine

A

Alpha 2 agonist

92
Q

Lofexidine

A

Alpha 2 agonist

93
Q

Methyldopa

A

Alpha 2 agonist

94
Q

Guanfacine

A

Alpha 2 agonist

95
Q

Dexmedetomidine

A

Alpha 2 agonist

96
Q

Brimonidine

Alphagan, mirvaso

A

Alpha 2 agonist

97
Q

Apraclonidine

A

Alpha 2 agonist

98
Q

Phentolamine

A

Non selective alpha adrenergic antagonist

Oraverse

99
Q

Phenoxybenzamine

A

irreversible non selective alpha adrenergic antagonist

100
Q

Metyrosine

A

Indirect acting sympatholytic

Inhibit tyrosine hydroxylase

101
Q

Reserpine

A

Indirect acting sympatholytics

Inhibit VMAT

Top 200 (17 decks)

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